Evaluation of the Activity and Tolerability of a Cosmetic Treatment for the Periocular Area on the Aging Face: Controlled Clinical and Instrumental Evaluation vs. Placebo
The aim of this study was to evaluate clinically and by non invasive instrumental evaluations the efficacy and tolerability of a cosmetic treatment containing an innovative active ingredient, ethyl ximenynate, in the prevention of dark circles under the eyes and blemishes of skin aging on the eye pr...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2014-05-01
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| Series: | Cosmetics |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2079-9284/1/2/105 |
| _version_ | 1818538428075081728 |
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| author | Adele Sparavigna Beatrice Tenconi Ileana De Ponti Giancarlo Guglielmini |
| author_facet | Adele Sparavigna Beatrice Tenconi Ileana De Ponti Giancarlo Guglielmini |
| author_sort | Adele Sparavigna |
| collection | DOAJ |
| description | The aim of this study was to evaluate clinically and by non invasive instrumental evaluations the efficacy and tolerability of a cosmetic treatment containing an innovative active ingredient, ethyl ximenynate, in the prevention of dark circles under the eyes and blemishes of skin aging on the eye profile. Evaluations were performed at baseline and after 2 and 4 weeks of treatment on 22 volunteers; the study was planned as a double blind half-face trial. Data showed a trend towards a lifting of the eyelid skin; all investigator scores (eye puffiness, skin smoothness, roughness and dryness) decreased. In addition, profilometric results confirmed the anti-wrinkles efficacy of the active product and its lifting action, while those related to spectrophotometry underlined the decongestant effect on dark circles that appeared, at the end of the study, to be less marked. The improvement of skin microcirculation and capillary resistance and vascular tone in the eye area underlines a general mitigation of all relevant skin imperfections and blemishes of skin aging on the eye profile. The active ingredient was shown to be effective for the cosmetic treatment of the periocular area. |
| first_indexed | 2024-12-11T21:28:51Z |
| format | Article |
| id | doaj.art-d5ad9683d56e48d28e708599e3e314ea |
| institution | Directory Open Access Journal |
| issn | 2079-9284 |
| language | English |
| last_indexed | 2024-12-11T21:28:51Z |
| publishDate | 2014-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cosmetics |
| spelling | doaj.art-d5ad9683d56e48d28e708599e3e314ea2022-12-22T00:50:15ZengMDPI AGCosmetics2079-92842014-05-011210511610.3390/cosmetics1020105cosmetics1020105Evaluation of the Activity and Tolerability of a Cosmetic Treatment for the Periocular Area on the Aging Face: Controlled Clinical and Instrumental Evaluation vs. PlaceboAdele Sparavigna0Beatrice Tenconi1Ileana De Ponti2Giancarlo Guglielmini3DermIng S.r.l. Clinical Research Institute, Viale Cesare Battisti 38, 20900 Monza, ItalyDermIng S.r.l. Clinical Research Institute, Viale Cesare Battisti 38, 20900 Monza, ItalyDermIng S.r.l. Clinical Research Institute, Viale Cesare Battisti 38, 20900 Monza, ItalySinerga SpA, Via della Pacciarna 67, 21050 Gorla Maggiore, ItalyThe aim of this study was to evaluate clinically and by non invasive instrumental evaluations the efficacy and tolerability of a cosmetic treatment containing an innovative active ingredient, ethyl ximenynate, in the prevention of dark circles under the eyes and blemishes of skin aging on the eye profile. Evaluations were performed at baseline and after 2 and 4 weeks of treatment on 22 volunteers; the study was planned as a double blind half-face trial. Data showed a trend towards a lifting of the eyelid skin; all investigator scores (eye puffiness, skin smoothness, roughness and dryness) decreased. In addition, profilometric results confirmed the anti-wrinkles efficacy of the active product and its lifting action, while those related to spectrophotometry underlined the decongestant effect on dark circles that appeared, at the end of the study, to be less marked. The improvement of skin microcirculation and capillary resistance and vascular tone in the eye area underlines a general mitigation of all relevant skin imperfections and blemishes of skin aging on the eye profile. The active ingredient was shown to be effective for the cosmetic treatment of the periocular area.http://www.mdpi.com/2079-9284/1/2/105circles under the eyeperiocular wrinkleseye profileethyl ximenynate |
| spellingShingle | Adele Sparavigna Beatrice Tenconi Ileana De Ponti Giancarlo Guglielmini Evaluation of the Activity and Tolerability of a Cosmetic Treatment for the Periocular Area on the Aging Face: Controlled Clinical and Instrumental Evaluation vs. Placebo Cosmetics circles under the eye periocular wrinkles eye profile ethyl ximenynate |
| title | Evaluation of the Activity and Tolerability of a Cosmetic Treatment for the Periocular Area on the Aging Face: Controlled Clinical and Instrumental Evaluation vs. Placebo |
| title_full | Evaluation of the Activity and Tolerability of a Cosmetic Treatment for the Periocular Area on the Aging Face: Controlled Clinical and Instrumental Evaluation vs. Placebo |
| title_fullStr | Evaluation of the Activity and Tolerability of a Cosmetic Treatment for the Periocular Area on the Aging Face: Controlled Clinical and Instrumental Evaluation vs. Placebo |
| title_full_unstemmed | Evaluation of the Activity and Tolerability of a Cosmetic Treatment for the Periocular Area on the Aging Face: Controlled Clinical and Instrumental Evaluation vs. Placebo |
| title_short | Evaluation of the Activity and Tolerability of a Cosmetic Treatment for the Periocular Area on the Aging Face: Controlled Clinical and Instrumental Evaluation vs. Placebo |
| title_sort | evaluation of the activity and tolerability of a cosmetic treatment for the periocular area on the aging face controlled clinical and instrumental evaluation vs placebo |
| topic | circles under the eye periocular wrinkles eye profile ethyl ximenynate |
| url | http://www.mdpi.com/2079-9284/1/2/105 |
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