Exercise reduces the anxiogenic effects of meta-chlorophenylpiperazine: The role of 5-HT2C receptors in the bed nucleus of the stria terminalis

Exercise reduces the anxiogenic effects of meta-chlorophenylpiperazine: The role of 5-HT2C receptors in the bed nucleus of the stria terminalis

IntroductionTwo weeks of voluntary exercise in group-housed mice produces a reduction in anxiety-like behaviors across a number of different measures, including a reduction in the anxiety levels typically produced by the anxiogenic serotonergic drug m-chlorophenylpiperazine (mCPP), an agonist at 5-H...

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Bibliographic Details
Main Authors: James H. Fox, Melissa N. Boucher, Khalil S. Abedrabbo, Brendan D. Hare, Bethany A. Grimmig, William A. Falls, Sayamwong E. Hammack
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
anxiety
serotonin
extended amygdala
stress
wheel running
Online Access:https://www.frontiersin.org/articles/10.3389/fnsyn.2022.1067420/full

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