NEW POSSIBILITIES IN PREOPERATiVE DIAGNOSIS OF NODULAR THYROID DISEASES
Galectin-3 (human Galectin-3 ELISA Bender MedSystems) was researched by the method of immune-enzyme analysis as an oncomarker in blood serum and. swabs of thyroid nodules of the patients with cancer (18) and. non-cancerous diseases of thyroid gland. (26) in the preoperative period. All the patients...
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Format: | Article |
Language: | Russian |
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Scientific Сentre for Family Health and Human Reproduction Problems
2012-07-01
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Series: | Acta Biomedica Scientifica |
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Online Access: | https://www.actabiomedica.ru/jour/article/view/968 |
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author | O. S. Olifirova S. V. Knalyan T. E. Talchenkova N. N. Trynov |
author_facet | O. S. Olifirova S. V. Knalyan T. E. Talchenkova N. N. Trynov |
author_sort | O. S. Olifirova |
collection | DOAJ |
description | Galectin-3 (human Galectin-3 ELISA Bender MedSystems) was researched by the method of immune-enzyme analysis as an oncomarker in blood serum and. swabs of thyroid nodules of the patients with cancer (18) and. non-cancerous diseases of thyroid gland. (26) in the preoperative period. All the patients with thyroid cancer had. galectin-3. Average levels of galectin-3 in patients with thyroid cancer in blood serum. (0,72 ± 0,1 ng/ml) and. swabs from the thyroid, nodules (2,86 ± 0,9 ng/ml) were significantly higher than similar indices at non-cancerous diseases (0,42 ± 0,19 and 0,83 ± 0,2 ng/ml respectively). Obtained results allow to suppose the possibility of determination, of galectin-3 as an additional parameter for the complex differential diagnosis of a highly differentiated thyroid cancer by the method of immune-enzyme analysis. |
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issn | 2541-9420 2587-9596 |
language | Russian |
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publishDate | 2012-07-01 |
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series | Acta Biomedica Scientifica |
spelling | doaj.art-d5b4bb6740fb4a7ba599e35a842c700c2024-03-28T07:49:06ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962012-07-0104(1)6367914NEW POSSIBILITIES IN PREOPERATiVE DIAGNOSIS OF NODULAR THYROID DISEASESO. S. Olifirova0S. V. Knalyan1T. E. Talchenkova2N. N. Trynov3Amur State Medical AcademyAmur State Medical AcademyAmur Regional Clinical HospitalAmur State Medical AcademyGalectin-3 (human Galectin-3 ELISA Bender MedSystems) was researched by the method of immune-enzyme analysis as an oncomarker in blood serum and. swabs of thyroid nodules of the patients with cancer (18) and. non-cancerous diseases of thyroid gland. (26) in the preoperative period. All the patients with thyroid cancer had. galectin-3. Average levels of galectin-3 in patients with thyroid cancer in blood serum. (0,72 ± 0,1 ng/ml) and. swabs from the thyroid, nodules (2,86 ± 0,9 ng/ml) were significantly higher than similar indices at non-cancerous diseases (0,42 ± 0,19 and 0,83 ± 0,2 ng/ml respectively). Obtained results allow to suppose the possibility of determination, of galectin-3 as an additional parameter for the complex differential diagnosis of a highly differentiated thyroid cancer by the method of immune-enzyme analysis.https://www.actabiomedica.ru/jour/article/view/968thyroid cancergalectin-3immune-enzyme analysis |
spellingShingle | O. S. Olifirova S. V. Knalyan T. E. Talchenkova N. N. Trynov NEW POSSIBILITIES IN PREOPERATiVE DIAGNOSIS OF NODULAR THYROID DISEASES Acta Biomedica Scientifica thyroid cancer galectin-3 immune-enzyme analysis |
title | NEW POSSIBILITIES IN PREOPERATiVE DIAGNOSIS OF NODULAR THYROID DISEASES |
title_full | NEW POSSIBILITIES IN PREOPERATiVE DIAGNOSIS OF NODULAR THYROID DISEASES |
title_fullStr | NEW POSSIBILITIES IN PREOPERATiVE DIAGNOSIS OF NODULAR THYROID DISEASES |
title_full_unstemmed | NEW POSSIBILITIES IN PREOPERATiVE DIAGNOSIS OF NODULAR THYROID DISEASES |
title_short | NEW POSSIBILITIES IN PREOPERATiVE DIAGNOSIS OF NODULAR THYROID DISEASES |
title_sort | new possibilities in preoperative diagnosis of nodular thyroid diseases |
topic | thyroid cancer galectin-3 immune-enzyme analysis |
url | https://www.actabiomedica.ru/jour/article/view/968 |
work_keys_str_mv | AT osolifirova newpossibilitiesinpreoperativediagnosisofnodularthyroiddiseases AT svknalyan newpossibilitiesinpreoperativediagnosisofnodularthyroiddiseases AT tetalchenkova newpossibilitiesinpreoperativediagnosisofnodularthyroiddiseases AT nntrynov newpossibilitiesinpreoperativediagnosisofnodularthyroiddiseases |