The Pattern of Pharmacological Treatment in Subjects with Metabolic Syndrome: Findings from Isfahan Healthy Heart Program

Background: Pharmacological therapy is a critical step in the management of individuals with Metabolic Syndrome (MetS) when lifestyle modifications can not to achieve the therapeutic goals. However, it is well-documented that other than weight loss, there is no single best therapy, and the treatment...

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Main Authors: Mojgan Gharipour, Afshan Akhavan TAbib, Nafiseh Toghianifar, Aliakbar Tavassoli, Amin Gharipour, Nizal Sarrafzadegan
Format: Article
Language:fas
Published: Isfahan University of Medical Sciences 2011-07-01
Series:مجله دانشکده پزشکی اصفهان
Subjects:
Online Access:http://jims.mui.ac.ir/index.php/jims/article/view/1011
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author Mojgan Gharipour
Afshan Akhavan TAbib
Nafiseh Toghianifar
Aliakbar Tavassoli
Amin Gharipour
Nizal Sarrafzadegan
author_facet Mojgan Gharipour
Afshan Akhavan TAbib
Nafiseh Toghianifar
Aliakbar Tavassoli
Amin Gharipour
Nizal Sarrafzadegan
author_sort Mojgan Gharipour
collection DOAJ
description Background: Pharmacological therapy is a critical step in the management of individuals with Metabolic Syndrome (MetS) when lifestyle modifications can not to achieve the therapeutic goals. However, it is well-documented that other than weight loss, there is no single best therapy, and the treatment should consist of treatment of individual components of the MetS. The objective of this study was to investigate treatment of individual components of the MetS among a population–based sample of individuals with the clustering of those components of the MetS. Methods: A cross-sectional population-based study, a randomly collected sample of men and women living in three counties in central Iran participating in the baseline survey of a community –based program in 2000-2001 were examined. A questionnaire was completed for all participants to collect data regarding their demographic characteristics, medical status and history of medication use. In this study we determined the association between clustering of MetS components and pharmacological treatment of cardiovascular risk factors. Finding: The most common pharmacologic agent received by individuals with MetS were beta blockers (72.8%) used for controlling high blood pressure, followed by lipid lowering agents (36%) without significant gender difference. Conclusion: Our results exhibited Beta blockers, statins, fibrates and glybenclamid are more prevalent drugs among subjects with metabolic syndrome. Further research is needed to better elucidate the compliance behavior of patients who have been diagnosed with MetS.
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spelling doaj.art-d5b4da47c25e46f2a8cb057ab19b5f1f2023-09-02T15:38:57ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2011-07-0129138562570673The Pattern of Pharmacological Treatment in Subjects with Metabolic Syndrome: Findings from Isfahan Healthy Heart ProgramMojgan Gharipour0Afshan Akhavan TAbib1Nafiseh Toghianifar2Aliakbar Tavassoli3Amin Gharipour4Nizal Sarrafzadegan5Researcher in Biochemistry, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, IranIsfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.Associate Professor. Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.Data mining Researcher, Isfahan Mathematics House, Isfahan, Iran.Professor, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.Background: Pharmacological therapy is a critical step in the management of individuals with Metabolic Syndrome (MetS) when lifestyle modifications can not to achieve the therapeutic goals. However, it is well-documented that other than weight loss, there is no single best therapy, and the treatment should consist of treatment of individual components of the MetS. The objective of this study was to investigate treatment of individual components of the MetS among a population–based sample of individuals with the clustering of those components of the MetS. Methods: A cross-sectional population-based study, a randomly collected sample of men and women living in three counties in central Iran participating in the baseline survey of a community –based program in 2000-2001 were examined. A questionnaire was completed for all participants to collect data regarding their demographic characteristics, medical status and history of medication use. In this study we determined the association between clustering of MetS components and pharmacological treatment of cardiovascular risk factors. Finding: The most common pharmacologic agent received by individuals with MetS were beta blockers (72.8%) used for controlling high blood pressure, followed by lipid lowering agents (36%) without significant gender difference. Conclusion: Our results exhibited Beta blockers, statins, fibrates and glybenclamid are more prevalent drugs among subjects with metabolic syndrome. Further research is needed to better elucidate the compliance behavior of patients who have been diagnosed with MetS.http://jims.mui.ac.ir/index.php/jims/article/view/1011Metabolic syndromeIranPharmacological treatment
spellingShingle Mojgan Gharipour
Afshan Akhavan TAbib
Nafiseh Toghianifar
Aliakbar Tavassoli
Amin Gharipour
Nizal Sarrafzadegan
The Pattern of Pharmacological Treatment in Subjects with Metabolic Syndrome: Findings from Isfahan Healthy Heart Program
مجله دانشکده پزشکی اصفهان
Metabolic syndrome
Iran
Pharmacological treatment
title The Pattern of Pharmacological Treatment in Subjects with Metabolic Syndrome: Findings from Isfahan Healthy Heart Program
title_full The Pattern of Pharmacological Treatment in Subjects with Metabolic Syndrome: Findings from Isfahan Healthy Heart Program
title_fullStr The Pattern of Pharmacological Treatment in Subjects with Metabolic Syndrome: Findings from Isfahan Healthy Heart Program
title_full_unstemmed The Pattern of Pharmacological Treatment in Subjects with Metabolic Syndrome: Findings from Isfahan Healthy Heart Program
title_short The Pattern of Pharmacological Treatment in Subjects with Metabolic Syndrome: Findings from Isfahan Healthy Heart Program
title_sort pattern of pharmacological treatment in subjects with metabolic syndrome findings from isfahan healthy heart program
topic Metabolic syndrome
Iran
Pharmacological treatment
url http://jims.mui.ac.ir/index.php/jims/article/view/1011
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