An Improved Concatenation of Deep Learning Models for Predicting and Interpreting Ischemic Stroke

Early detection of stroke warning symptoms can help reduce the severity of ischemic stroke, the leading cause of mortality and disability worldwide. This study aims to develop a model to predict the disease by leveraging machine learning-based models. A model that concatenates a convolutional neural...

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Main Authors: Sapiah Sakri, Shakila Basheer, Zuhaira Muhammad Zain, Nurul Halimatul Asmak Ismail, Dua' Abdellatef Nassar, Ghadah Nasser Aldehim, Mais Ayman Alharaki
Format: Article
Language:English
Published: IEEE 2024-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/10494753/
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author Sapiah Sakri
Shakila Basheer
Zuhaira Muhammad Zain
Nurul Halimatul Asmak Ismail
Dua' Abdellatef Nassar
Ghadah Nasser Aldehim
Mais Ayman Alharaki
author_facet Sapiah Sakri
Shakila Basheer
Zuhaira Muhammad Zain
Nurul Halimatul Asmak Ismail
Dua' Abdellatef Nassar
Ghadah Nasser Aldehim
Mais Ayman Alharaki
author_sort Sapiah Sakri
collection DOAJ
description Early detection of stroke warning symptoms can help reduce the severity of ischemic stroke, the leading cause of mortality and disability worldwide. This study aims to develop a model to predict the disease by leveraging machine learning-based models. A model that concatenates a convolutional neural network and a long short-term memory was developed as the proposed model. Seven other classifiers were treated as the baseline models: logistic regression, random forest, extreme gradient boosting, k-nearest neighbor, artificial neural network, long short-term memory, and convolutional neural network. All models were trained using a healthcare dataset of 5110 patients’ health profiles. A synthetic minority oversampling technique was deployed to balance the data. Metrics such as accuracy, precision, F1-score, recall, area under the curve, and confusion metrics were used to evaluate the models’ performance. With a 95.9% accuracy, the proposed model outperformed the models employed in this study and improved the accuracy of prior studies that used the same dataset. The Shapley Additive Explanations method was applied to explain the result obtained by the best model. The proposed model was created to predict ischemic stroke. It considers each patient’s profile, allowing for personalized decision-making in resource-constrained settings.
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spelling doaj.art-d5b667c1d7ab4b7b80fcb8200047f60c2024-04-22T23:00:34ZengIEEEIEEE Access2169-35362024-01-0112531895320410.1109/ACCESS.2024.338622010494753An Improved Concatenation of Deep Learning Models for Predicting and Interpreting Ischemic StrokeSapiah Sakri0https://orcid.org/0000-0001-5034-2752Shakila Basheer1https://orcid.org/0000-0001-9032-9560Zuhaira Muhammad Zain2https://orcid.org/0000-0002-5973-387XNurul Halimatul Asmak Ismail3https://orcid.org/0000-0002-2222-5644Dua' Abdellatef Nassar4Ghadah Nasser Aldehim5https://orcid.org/0000-0002-5511-8909Mais Ayman Alharaki6https://orcid.org/0000-0002-4793-8544Department of Information Systems, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi ArabiaDepartment of Information Systems, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi ArabiaDepartment of Information Systems, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi ArabiaDepartment of Computer Science and Information Technology, Applied College, Princess Nourah bint Abdulrahman University, Riyadh, Saudi ArabiaDepartment of Information Systems, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi ArabiaDepartment of Information Systems, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi ArabiaDepartment of Information Systems, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi ArabiaEarly detection of stroke warning symptoms can help reduce the severity of ischemic stroke, the leading cause of mortality and disability worldwide. This study aims to develop a model to predict the disease by leveraging machine learning-based models. A model that concatenates a convolutional neural network and a long short-term memory was developed as the proposed model. Seven other classifiers were treated as the baseline models: logistic regression, random forest, extreme gradient boosting, k-nearest neighbor, artificial neural network, long short-term memory, and convolutional neural network. All models were trained using a healthcare dataset of 5110 patients’ health profiles. A synthetic minority oversampling technique was deployed to balance the data. Metrics such as accuracy, precision, F1-score, recall, area under the curve, and confusion metrics were used to evaluate the models’ performance. With a 95.9% accuracy, the proposed model outperformed the models employed in this study and improved the accuracy of prior studies that used the same dataset. The Shapley Additive Explanations method was applied to explain the result obtained by the best model. The proposed model was created to predict ischemic stroke. It considers each patient’s profile, allowing for personalized decision-making in resource-constrained settings.https://ieeexplore.ieee.org/document/10494753/Ischemic stroke predictionSHAP methodhybrid deep learning modelmachine learning
spellingShingle Sapiah Sakri
Shakila Basheer
Zuhaira Muhammad Zain
Nurul Halimatul Asmak Ismail
Dua' Abdellatef Nassar
Ghadah Nasser Aldehim
Mais Ayman Alharaki
An Improved Concatenation of Deep Learning Models for Predicting and Interpreting Ischemic Stroke
IEEE Access
Ischemic stroke prediction
SHAP method
hybrid deep learning model
machine learning
title An Improved Concatenation of Deep Learning Models for Predicting and Interpreting Ischemic Stroke
title_full An Improved Concatenation of Deep Learning Models for Predicting and Interpreting Ischemic Stroke
title_fullStr An Improved Concatenation of Deep Learning Models for Predicting and Interpreting Ischemic Stroke
title_full_unstemmed An Improved Concatenation of Deep Learning Models for Predicting and Interpreting Ischemic Stroke
title_short An Improved Concatenation of Deep Learning Models for Predicting and Interpreting Ischemic Stroke
title_sort improved concatenation of deep learning models for predicting and interpreting ischemic stroke
topic Ischemic stroke prediction
SHAP method
hybrid deep learning model
machine learning
url https://ieeexplore.ieee.org/document/10494753/
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