Alternative splicing of LSD1+8a in neuroendocrine prostate cancer is mediated by SRRM4

Alternative splicing of LSD1+8a in neuroendocrine prostate cancer is mediated by SRRM4

Neuroendocrine prostate cancer (NEPC) is the most virulent form of prostate cancer. Importantly, our recent work examining metastatic biopsy samples demonstrates NEPC is increasing in frequency. In contrast to prostate adenocarcinomas that express a luminal gene expression program, NEPC tumors expre...

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Bibliographic Details
Main Authors: Daniel J. Coleman, David A. Sampson, Archana Sehrawat, Anbarasu Kumaraswamy, Duanchen Sun, Yuzhuo Wang, Jacob Schwartzman, Joshua Urrutia, Ahn R. Lee, Ilsa M. Coleman, Peter S. Nelson, Xuesen Dong, Colm Morrissey, Eva Corey, Zheng Xia, Joel A. Yates, Joshi J. Alumkal
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Neuroendocrine prostate cancer
LSD1
LSD1+8a
SRRM4
Epigenetics
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558620301147

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