Diagnosis of hypertension: Ambulatory pediatric American Heart Association/European Society of Hypertension versus blood pressure load thresholds

Abstract The agreement between the traditionally‐used ambulatory blood pressure (ABP)‐load thresholds in children and recently‐recommended pediatric American Heart Association (AHA)/European Society of Hypertension (ESH) ABP thresholds for diagnosing ambulatory hypertension (AH), white coat hyperten...

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Main Authors: Ajay P. Sharma, Luis Altamirano‐Diaz, Mohamed Mohamed Ali, Katryna Stronks, Amrit Kirpalani, Guido Filler, Kambiz Norozi
Format: Article
Language:English
Published: Wiley 2021-11-01
Series:The Journal of Clinical Hypertension
Subjects:
Online Access:https://doi.org/10.1111/jch.14368
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author Ajay P. Sharma
Luis Altamirano‐Diaz
Mohamed Mohamed Ali
Katryna Stronks
Amrit Kirpalani
Guido Filler
Kambiz Norozi
author_facet Ajay P. Sharma
Luis Altamirano‐Diaz
Mohamed Mohamed Ali
Katryna Stronks
Amrit Kirpalani
Guido Filler
Kambiz Norozi
author_sort Ajay P. Sharma
collection DOAJ
description Abstract The agreement between the traditionally‐used ambulatory blood pressure (ABP)‐load thresholds in children and recently‐recommended pediatric American Heart Association (AHA)/European Society of Hypertension (ESH) ABP thresholds for diagnosing ambulatory hypertension (AH), white coat hypertension (WCH), and masked hypertension (MH) has not been evaluated. In this cross‐sectional study on 450 outpatient participants, the authors evaluated the agreement between previously used ABP‐load 25%, 30%, 40%, 50% thresholds and the AHA/ESH thresholds for diagnosing AH, WCH, and MH. The American Academy of Pediatrics thresholds were used to diagnose office hypertension. The AHA threshold diagnosed ambulatory normotension/hypertension closest to ABP load 50% in 88% (95% CI 0.79, 0.96) participants (k 0.67, 95% CI 0.59, 0.75) and the ESH threshold diagnosed ambulatory normotension/hypertension closest to ABP load 40% in 86% (95% CI 0.77, 0.94) participants (k 0.66, 95% CI 0.59, 0.74). In contrast, the AHA/ESH thresholds had a relatively weaker agreement with ABP load 25%/30%. Therefore, the diagnosis of AH was closest between the AHA threshold and ABP load 50% (difference 3%, 95% CI ‐2.6%, 8.6%, p = .29) and between the ESH threshold and ABP load 40% (difference 4%, 95% CI ‐2.1%, 10.1%, p = .19) than between the AHA/ESH and ABP load 25%/30% thresholds. A similar agreement pattern persisted between the AHA/ESH and various ABP load thresholds for diagnosing WCH and MH. The AHA and ESH thresholds diagnosed AH, WCH, and MH closest to ABP load 40%/50% than ABP load 25%/30%. Future outcome‐based studies are needed to guide the optimal use of these ABP thresholds in clinical practice.
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spelling doaj.art-d5bc10bb70cf4f0cb1d82ee622b3868e2023-10-30T13:30:54ZengWileyThe Journal of Clinical Hypertension1524-61751751-71762021-11-0123111947195610.1111/jch.14368Diagnosis of hypertension: Ambulatory pediatric American Heart Association/European Society of Hypertension versus blood pressure load thresholdsAjay P. Sharma0Luis Altamirano‐Diaz1Mohamed Mohamed Ali2Katryna Stronks3Amrit Kirpalani4Guido Filler5Kambiz Norozi6University of Western Ontario London Ontario CanadaUniversity of Western Ontario London Ontario CanadaUniversity of Western Ontario London Ontario CanadaUniversity of Western Ontario London Ontario CanadaUniversity of Western Ontario London Ontario CanadaUniversity of Western Ontario London Ontario CanadaUniversity of Western Ontario London Ontario CanadaAbstract The agreement between the traditionally‐used ambulatory blood pressure (ABP)‐load thresholds in children and recently‐recommended pediatric American Heart Association (AHA)/European Society of Hypertension (ESH) ABP thresholds for diagnosing ambulatory hypertension (AH), white coat hypertension (WCH), and masked hypertension (MH) has not been evaluated. In this cross‐sectional study on 450 outpatient participants, the authors evaluated the agreement between previously used ABP‐load 25%, 30%, 40%, 50% thresholds and the AHA/ESH thresholds for diagnosing AH, WCH, and MH. The American Academy of Pediatrics thresholds were used to diagnose office hypertension. The AHA threshold diagnosed ambulatory normotension/hypertension closest to ABP load 50% in 88% (95% CI 0.79, 0.96) participants (k 0.67, 95% CI 0.59, 0.75) and the ESH threshold diagnosed ambulatory normotension/hypertension closest to ABP load 40% in 86% (95% CI 0.77, 0.94) participants (k 0.66, 95% CI 0.59, 0.74). In contrast, the AHA/ESH thresholds had a relatively weaker agreement with ABP load 25%/30%. Therefore, the diagnosis of AH was closest between the AHA threshold and ABP load 50% (difference 3%, 95% CI ‐2.6%, 8.6%, p = .29) and between the ESH threshold and ABP load 40% (difference 4%, 95% CI ‐2.1%, 10.1%, p = .19) than between the AHA/ESH and ABP load 25%/30% thresholds. A similar agreement pattern persisted between the AHA/ESH and various ABP load thresholds for diagnosing WCH and MH. The AHA and ESH thresholds diagnosed AH, WCH, and MH closest to ABP load 40%/50% than ABP load 25%/30%. Future outcome‐based studies are needed to guide the optimal use of these ABP thresholds in clinical practice.https://doi.org/10.1111/jch.14368ambulatory blood pressure monitoringhypertension diagnosismasked hypertensionpediatric blood pressurepediatric hypertensionwhite coat hypertension
spellingShingle Ajay P. Sharma
Luis Altamirano‐Diaz
Mohamed Mohamed Ali
Katryna Stronks
Amrit Kirpalani
Guido Filler
Kambiz Norozi
Diagnosis of hypertension: Ambulatory pediatric American Heart Association/European Society of Hypertension versus blood pressure load thresholds
The Journal of Clinical Hypertension
ambulatory blood pressure monitoring
hypertension diagnosis
masked hypertension
pediatric blood pressure
pediatric hypertension
white coat hypertension
title Diagnosis of hypertension: Ambulatory pediatric American Heart Association/European Society of Hypertension versus blood pressure load thresholds
title_full Diagnosis of hypertension: Ambulatory pediatric American Heart Association/European Society of Hypertension versus blood pressure load thresholds
title_fullStr Diagnosis of hypertension: Ambulatory pediatric American Heart Association/European Society of Hypertension versus blood pressure load thresholds
title_full_unstemmed Diagnosis of hypertension: Ambulatory pediatric American Heart Association/European Society of Hypertension versus blood pressure load thresholds
title_short Diagnosis of hypertension: Ambulatory pediatric American Heart Association/European Society of Hypertension versus blood pressure load thresholds
title_sort diagnosis of hypertension ambulatory pediatric american heart association european society of hypertension versus blood pressure load thresholds
topic ambulatory blood pressure monitoring
hypertension diagnosis
masked hypertension
pediatric blood pressure
pediatric hypertension
white coat hypertension
url https://doi.org/10.1111/jch.14368
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