Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia
A new bisbenzylisoquinoline, lancifoliaine (1), together with seven known alkaloids – N-allyllaurolitsine (2), reticuline (3), actinodaphnine, norboldine, pallidine, cassythicine and boldine – were isolated from the stem bark of Litsea lancifolia (Lauraceae). In addition to that of lancifoliaine, co...
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2011-04-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/16/4/3119/ |
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| author | Kazumasa Zaima Marc Litaudon Azeana Zahari Hazrina Hazni A Hamid A Hadi Khalijah Awang Mat Ropi Mukhtar Syazreen Nadia Sulaiman Hiroshi Morita |
| author_facet | Kazumasa Zaima Marc Litaudon Azeana Zahari Hazrina Hazni A Hamid A Hadi Khalijah Awang Mat Ropi Mukhtar Syazreen Nadia Sulaiman Hiroshi Morita |
| author_sort | Kazumasa Zaima |
| collection | DOAJ |
| description | A new bisbenzylisoquinoline, lancifoliaine (1), together with seven known alkaloids – N-allyllaurolitsine (2), reticuline (3), actinodaphnine, norboldine, pallidine, cassythicine and boldine – were isolated from the stem bark of Litsea lancifolia (Lauraceae). In addition to that of lancifoliaine, complete 13C-NMR data of N-allyl-laurolitsine (2) was also reported. The alkaloidal structures were elucidated by means of high field 1D- and 2D-NMR IR, UV, and LCMS-IT-TOF spectral data. N-Allyllaurolitsine (2) showed a moderate vasorelaxant activity on isolated rat aorta. |
| first_indexed | 2024-04-13T12:06:30Z |
| format | Article |
| id | doaj.art-d5c9c7f008e3464fb13a40deb67abe86 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-04-13T12:06:30Z |
| publishDate | 2011-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-d5c9c7f008e3464fb13a40deb67abe862022-12-22T02:47:38ZengMDPI AGMolecules1420-30492011-04-011643119312710.3390/molecules16043119Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifoliaKazumasa ZaimaMarc LitaudonAzeana ZahariHazrina HazniA Hamid A HadiKhalijah AwangMat Ropi MukhtarSyazreen Nadia SulaimanHiroshi MoritaA new bisbenzylisoquinoline, lancifoliaine (1), together with seven known alkaloids – N-allyllaurolitsine (2), reticuline (3), actinodaphnine, norboldine, pallidine, cassythicine and boldine – were isolated from the stem bark of Litsea lancifolia (Lauraceae). In addition to that of lancifoliaine, complete 13C-NMR data of N-allyl-laurolitsine (2) was also reported. The alkaloidal structures were elucidated by means of high field 1D- and 2D-NMR IR, UV, and LCMS-IT-TOF spectral data. N-Allyllaurolitsine (2) showed a moderate vasorelaxant activity on isolated rat aorta.http://www.mdpi.com/1420-3049/16/4/3119/bisbenzylisoquinolinelancifoliaineN-allyllaurolitsineLauraceaevaso-relaxant activity |
| spellingShingle | Kazumasa Zaima Marc Litaudon Azeana Zahari Hazrina Hazni A Hamid A Hadi Khalijah Awang Mat Ropi Mukhtar Syazreen Nadia Sulaiman Hiroshi Morita Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia Molecules bisbenzylisoquinoline lancifoliaine N-allyllaurolitsine Lauraceae vaso-relaxant activity |
| title | Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia |
| title_full | Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia |
| title_fullStr | Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia |
| title_full_unstemmed | Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia |
| title_short | Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia |
| title_sort | lancifoliaine a new bisbenzylisoquinoline from the bark of litsea lancifolia |
| topic | bisbenzylisoquinoline lancifoliaine N-allyllaurolitsine Lauraceae vaso-relaxant activity |
| url | http://www.mdpi.com/1420-3049/16/4/3119/ |
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