Prevalence and risk factors of functional gastrointestinal disorders in Vietnamese infants and young children
Abstract Background Functional gastrointestinal disorders (FGIDs) are common early in life. The prevalence of FGIDs varies among countries but is unknown in Vietnam. The aim of this study is to assess the prevalence of FGIDs in healthy Vietnamese infants and young children. Methods This was a cross-...
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| Format: | Article |
| Language: | English |
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BMC
2022-05-01
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| Series: | BMC Pediatrics |
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| Online Access: | https://doi.org/10.1186/s12887-022-03378-z |
| _version_ | 1811258682400309248 |
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| author | Loo Wee Chia Thi Viet Ha Nguyen Van Nha Phan Thi Thao Nguyen Luu Gia Khanh Nguyen Serene Yaling Tan Shaman Rajindrajith Marc Alexander Benninga |
| author_facet | Loo Wee Chia Thi Viet Ha Nguyen Van Nha Phan Thi Thao Nguyen Luu Gia Khanh Nguyen Serene Yaling Tan Shaman Rajindrajith Marc Alexander Benninga |
| author_sort | Loo Wee Chia |
| collection | DOAJ |
| description | Abstract Background Functional gastrointestinal disorders (FGIDs) are common early in life. The prevalence of FGIDs varies among countries but is unknown in Vietnam. The aim of this study is to assess the prevalence of FGIDs in healthy Vietnamese infants and young children. Methods This was a cross-sectional, observational study involving healthy infants and young children between 0 – 48 months old in Hanoi, Vietnam. A representative total of 1511 subjects completed the validated questionnaire on paediatric FGIDs. Rome IV criteria were used to define FGIDs. Results For Vietnamese infants (0–6 months) and young children (7–48 months), the prevalence of having at least one FGID was 10.0% and only 0.6% was having more than one FGID. Infantile regurgitation (9.3%) was the most prevalent FGID among infants 0—6 months of age while all other FGIDs had a low prevalence between 0—2.5%. For young children between 7 – 48 months old, functional constipation was the most common disorder at the rate of 5.6%. Association analysis revealed that the risk of infant regurgitation was significantly lower among infants with exclusively breastfeeding at 2 – 3 months and 3 – 4 months, formula initiation at 0 – 1 months, and higher paternal education level. The prevalence of functional constipation was significantly higher in male subjects, children in families with annual household income between 273,000,000 – 546,999,999 VND (or estimate around 11,800 – 23,800 USD), families with one child only, and formula feeding initiation at 1 – 2 months. Conclusions The prevalence of FGIDs in Vietnamese infants and young children is relatively low compared to the published literature using Rome IV diagnostic criteria. Infantile regurgitation was the most common FGID in Vietnamese infants while functional constipation was most prevalent among Vietnamese young children. Trial registration Netherlands Trial Registry Identifier: NL7286/NTR7495 . |
| first_indexed | 2024-04-12T18:18:17Z |
| format | Article |
| id | doaj.art-d5cbe5f5a08c4b5fbdadea6358628eae |
| institution | Directory Open Access Journal |
| issn | 1471-2431 |
| language | English |
| last_indexed | 2024-04-12T18:18:17Z |
| publishDate | 2022-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pediatrics |
| spelling | doaj.art-d5cbe5f5a08c4b5fbdadea6358628eae2022-12-22T03:21:32ZengBMCBMC Pediatrics1471-24312022-05-012211710.1186/s12887-022-03378-zPrevalence and risk factors of functional gastrointestinal disorders in Vietnamese infants and young childrenLoo Wee Chia0Thi Viet Ha Nguyen1Van Nha Phan2Thi Thao Nguyen Luu3Gia Khanh Nguyen4Serene Yaling Tan5Shaman Rajindrajith6Marc Alexander Benninga7FrieslandCampinaDepartment of Paediatrics, Hanoi Medical UniversityDepartment of Paediatrics, Hanoi Medical UniversityDepartment of Paediatrics, Hanoi Medical UniversityNational Paediatric Association VietnamFrieslandCampinaDepartment of Paediatrics, Faculty of Medicine, University of ColomboDepartment of Paediatric Gastroenterology, Emma Children’s Hospital, Amsterdam University Medical CentresAbstract Background Functional gastrointestinal disorders (FGIDs) are common early in life. The prevalence of FGIDs varies among countries but is unknown in Vietnam. The aim of this study is to assess the prevalence of FGIDs in healthy Vietnamese infants and young children. Methods This was a cross-sectional, observational study involving healthy infants and young children between 0 – 48 months old in Hanoi, Vietnam. A representative total of 1511 subjects completed the validated questionnaire on paediatric FGIDs. Rome IV criteria were used to define FGIDs. Results For Vietnamese infants (0–6 months) and young children (7–48 months), the prevalence of having at least one FGID was 10.0% and only 0.6% was having more than one FGID. Infantile regurgitation (9.3%) was the most prevalent FGID among infants 0—6 months of age while all other FGIDs had a low prevalence between 0—2.5%. For young children between 7 – 48 months old, functional constipation was the most common disorder at the rate of 5.6%. Association analysis revealed that the risk of infant regurgitation was significantly lower among infants with exclusively breastfeeding at 2 – 3 months and 3 – 4 months, formula initiation at 0 – 1 months, and higher paternal education level. The prevalence of functional constipation was significantly higher in male subjects, children in families with annual household income between 273,000,000 – 546,999,999 VND (or estimate around 11,800 – 23,800 USD), families with one child only, and formula feeding initiation at 1 – 2 months. Conclusions The prevalence of FGIDs in Vietnamese infants and young children is relatively low compared to the published literature using Rome IV diagnostic criteria. Infantile regurgitation was the most common FGID in Vietnamese infants while functional constipation was most prevalent among Vietnamese young children. Trial registration Netherlands Trial Registry Identifier: NL7286/NTR7495 .https://doi.org/10.1186/s12887-022-03378-zColicConstipationDiarrhoeaDyscheziaPaediatricRegurgitation |
| spellingShingle | Loo Wee Chia Thi Viet Ha Nguyen Van Nha Phan Thi Thao Nguyen Luu Gia Khanh Nguyen Serene Yaling Tan Shaman Rajindrajith Marc Alexander Benninga Prevalence and risk factors of functional gastrointestinal disorders in Vietnamese infants and young children BMC Pediatrics Colic Constipation Diarrhoea Dyschezia Paediatric Regurgitation |
| title | Prevalence and risk factors of functional gastrointestinal disorders in Vietnamese infants and young children |
| title_full | Prevalence and risk factors of functional gastrointestinal disorders in Vietnamese infants and young children |
| title_fullStr | Prevalence and risk factors of functional gastrointestinal disorders in Vietnamese infants and young children |
| title_full_unstemmed | Prevalence and risk factors of functional gastrointestinal disorders in Vietnamese infants and young children |
| title_short | Prevalence and risk factors of functional gastrointestinal disorders in Vietnamese infants and young children |
| title_sort | prevalence and risk factors of functional gastrointestinal disorders in vietnamese infants and young children |
| topic | Colic Constipation Diarrhoea Dyschezia Paediatric Regurgitation |
| url | https://doi.org/10.1186/s12887-022-03378-z |
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