Oxidation of the albumin thiol to sulfenic acid and its implications in the intravascular compartment

Oxidation of the albumin thiol to sulfenic acid and its implications in the intravascular compartment

Human serum albumin (HSA) is the most abundant protein in the intravascular compartment. It possesses a single thiol, Cys34, which constitutes ~80% of the total thiols in plasma. This thiol is able to scavenge plasma oxidants. A central intermediate in this potential antioxidant activity of human se...

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Bibliographic Details
Main Authors:	L. Turell, S. Carballal, H. Botti, R. Radi, B. Alvarez
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2009-04-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Thiol Sulfhydryl Albumin Sulfenic acid Mixed disulfides Plasma
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000400001

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