Endogenous opioids regulate moment-to-moment neuronal communication and excitability

Endogenous opioids regulate moment-to-moment neuronal communication and excitability

The endogenous opioid system regulates fear and anxiety, but the underlying cellular mechanism is unclear. Winterset al. shows that in the intercalated cells (ITC) of the amygdala, endogenous opioids suppress glutamatergic inputs via the δ-opioid receptor presynaptically, and reduce the excitability...

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Bibliographic Details
Main Authors: Bryony L. Winters, Gabrielle C. Gregoriou, Sarah A. Kissiwaa, Oliver A. Wells, Danashi I. Medagoda, Sam M. Hermes, Neil T. Burford, Andrew Alt, Sue A. Aicher, Elena E. Bagley
Format: Article
Language:English
Published: Nature Portfolio 2017-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14611

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