Down-Regulation of CIDEA Promoted Tumor Growth and Contributed to Cisplatin Resistance by Regulating the JNK-p21/Bad Signaling Pathways in Esophageal Squamous Cell Carcinoma

Down-Regulation of CIDEA Promoted Tumor Growth and Contributed to Cisplatin Resistance by Regulating the JNK-p21/Bad Signaling Pathways in Esophageal Squamous Cell Carcinoma

Esophageal squamous cell carcinoma (ESCC) is one of the most common malignancies with poor prognosis and lack of effective targeted therapies. In this study, we investigated the tumor suppressive role of the cell death inducing DFF like effector A (CIDEA) in ESCC. Firstly, public datasets and ESCC t...

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Bibliographic Details
Main Authors: Ya-Ping Gao, Lei Li, Jie Yan, Xiao-Xia Hou, Yong-Xu Jia, Zhi-Wei Chang, Xin-Yuan Guan, Yan-Ru Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
esophageal squamous cell carcinoma
cell death inducing DFF like effector A
methylation
cisplatin
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.627845/full

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