Natural Compounds in Sex Hormone-Dependent Cancers: The Role of Triterpenes as Therapeutic Agents

Natural Compounds in Sex Hormone-Dependent Cancers: The Role of Triterpenes as Therapeutic Agents

Sex hormone-dependent cancers currently contribute to the high number of cancer-related deaths worldwide. The study and elucidation of the molecular mechanisms underlying the progression of these tumors was a double-edged sword, leading to the expansion and development of new treatment options, with...

Full description

Bibliographic Details
Main Authors:	Codruţa Şoica, Mirela Voicu, Roxana Ghiulai, Cristina Dehelean, Roxana Racoviceanu, Cristina Trandafirescu, Oana-Janina Roșca, Gabriela Nistor, Marius Mioc, Alexandra Mioc
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-01-01
Series:	Frontiers in Endocrinology
Subjects:	phytocompounds triterpenes hormone-dependent cancers antiproliferative activity therapeutic agents
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2020.612396/full

Similar Items

The Role of Cyclodextrins in the Design and Development of Triterpene-Based Therapeutic Agents
by: Alexandra Prodea, et al.
Published: (2022-01-01)

Tetracyclic and Pentacyclic Triterpenes with High Therapeutic Efficiency in Wound Healing Approaches
by: Roxana Ghiulai, et al.
Published: (2020-11-01)

Semisynthetic Derivatives of Pentacyclic Triterpenes Bearing Heterocyclic Moieties with Therapeutic Potential
by: Gabriela Nistor, et al.
Published: (2022-10-01)

Recent Advances Regarding the Molecular Mechanisms of Triterpenic Acids: A Review (Part II)
by: Marius Mioc, et al.
Published: (2022-08-01)

The Optimized Delivery of Triterpenes by Liposomal Nanoformulations: Overcoming the Challenges
by: Andreea Milan, et al.
Published: (2022-01-01)

Novel Triterpenic Acid—Benzotriazole Esters Act as Pro-Apoptotic Antimelanoma Agents
by: Marius Mioc, et al.
Published: (2022-09-01)

Recent Advances Regarding the Molecular Mechanisms of Triterpenic Acids: A Review (Part I)
by: Marius Mioc, et al.
Published: (2022-07-01)

The C30-Modulation of Betulinic Acid Using 1,2,4-Triazole: A Promising Strategy for Increasing Its Antimelanoma Cytotoxic Potential
by: Gabriela Nistor, et al.
Published: (2022-11-01)

3-Pyridinylidene Derivatives of Chemically Modified Lupane and Ursane Triterpenes as Promising Anticancer Agents by Targeting Apoptosis
by: Oxana Kazakova, et al.
Published: (2021-10-01)

The Antimelanoma Biological Assessment of Triterpenic Acid Functionalized Gold Nanoparticles
by: Marius Mioc, et al.
Published: (2023-01-01)

Cocrystal Formation of Betulinic Acid and Ascorbic Acid: Synthesis, Physico-Chemical Assessment, Antioxidant, and Antiproliferative Activity
by: Mirela Nicolov, et al.
Published: (2019-02-01)

The Anti-Melanoma Effect of Betulinic Acid Functionalized Gold Nanoparticles: A Mechanistic In Vitro Approach
by: Roxana Ghiulai, et al.
Published: (2022-11-01)

Design, Synthesis and Biological Activity Evaluation of S-Substituted 1H-5-Mercapto-1,2,4-Triazole Derivatives as Antiproliferative Agents in Colorectal Cancer
by: Marius Mioc, et al.
Published: (2018-08-01)

Newly Synthesized CoFe<sub>2−x</sub>Dy<sub>x</sub>O<sub>4</sub> (x = 0; 0.1; 0.2; 0.4) Nanoparticles Reveal Promising Anticancer Activity against Melanoma (A375) and Breast Cancer (MCF-7) Cells
by: Slaviţa Rotunjanu, et al.
Published: (2023-10-01)

Solid Polymeric Nanoparticles of Albendazole: Synthesis, Physico-Chemical Characterization and Biological Activity
by: Roxana Racoviceanu, et al.
Published: (2020-11-01)

Total phenolic content, FTIR analysis, and antiproliferative evaluation of lupin seeds harvest from western Romania
by: Corina Danciu, et al.
Published: (2017-12-01)

Vegetal Compounds as Sources of Prophylactic and Therapeutic Agents in Dentistry
by: Raluca-Adriana Milutinovici, et al.
Published: (2021-10-01)

Triterpenes as Potentially Cytotoxic Compounds
by: Malwina Chudzik, et al.
Published: (2015-01-01)

Characterization of a Pentacyclic Triterpene Acetyltransferase Involved in the Biosynthesis of Taraxasterol and ψ-Taraxasterol Acetates in Lettuce
by: Han Suk Choi, et al.
Published: (2022-01-01)

Actaticas A−G, Cycloartane Triterpenes From Actaea asiatica With Their Antiproliferative Activity
by: Meigeng Hu, et al.
Published: (2021-07-01)

Structural Investigation of Betulinic Acid Plasma Metabolites by Tandem Mass Spectrometry
by: Roxana Ghiulai, et al.
Published: (2022-10-01)

Fe<sub>3</sub>O<sub>4</sub>-PAA–(HP-γ-CDs) Biocompatible Ferrimagnetic Nanoparticles for Increasing the Efficacy in Superparamagnetic Hyperthermia
by: Costica Caizer, et al.
Published: (2022-07-01)

Bioactive triterpenes and phenolics of leaves of Eugenia brasiliensis
by: Michele Debiase Alberton Magina, et al.
Published: (2012-01-01)

The Triterpenes of Kageneckia oblonga
by: Jorge Tapia-Merino, et al.
Published: (2022-08-01)

Triterpenes from Minquartia guianensis (Olacaceae) and in vitro antimalarial activity
by: Lorena Mayara de Carvalho Cursino, et al.
Published: (2012-01-01)

Triterpenes and antitubercular activity of Byrsonima crassa
by: Celio Takashi Higuchi, et al.
Published: (2008-01-01)

Triterpenes from Kadsura coccinea
by: Hai-Xia Li, et al.
Published: (2012-04-01)

Design and Assessment of a Polyurethane Carrier Used for the Transmembrane Transfer of Acyclovir
by: Florin Borcan, et al.
Published: (2020-12-01)

New Cytotoxic Seco-Type Triterpene and Labdane-Type Diterpenes from Nuxia oppositifolia
by: Shaza M. Al-Massarani, et al.
Published: (2017-03-01)

Protostane and Fusidane Triterpenes: A Mini-Review
by: Chun-Tao Che, et al.
Published: (2013-04-01)

Phytochemical Analysis of Podospermum and Scorzonera n-Hexane Extracts and the HPLC Quantitation of Triterpenes
by: Özlem Bahadır-Acıkara, et al.
Published: (2018-07-01)

Pentacyclic Triterpene Bioavailability: An Overview of In Vitro and In Vivo Studies
by: Niege A. J. C. Furtado, et al.
Published: (2017-03-01)

Triterpene Content in Flesh and Peel of Apples Grown on Different Rootstocks
by: Aurita Butkevičiūtė, et al.
Published: (2022-05-01)

Triterpenes and new saponins from Ilex chamaedryfolia: chemotaxonomic tool to ilex species differentiation
by: Claiton L. Lencina, et al.
Published: (2011-01-01)

Antifungal iridoids, triterpenes and phenol compounds from Alibertia myrciifolia Sprunge Ex. Schum
by: João Henrique S. Luciano, et al.
Published: (2010-01-01)

Plant-Growth-Promoting Rhizobacteria Improve Germination and Bioactive Compounds in Cucumber Seedlings
by: Laura-Andrea Pérez-García, et al.
Published: (2023-01-01)

In Vivo Antihyperglycemic Activity of a Lanosteryl Triterpene from Protorhus longifolia
by: Rebamang A. Mosa, et al.
Published: (2015-07-01)

Steroidal Triterpenes of Cholesterol Synthesis
by: Damjana Rozman, et al.
Published: (2013-04-01)

Bioactive Pentacyclic Triterpenes from the Stems of Combretum laxum
by: Eder Bisoli, et al.
Published: (2008-11-01)

Comprehensive metabolic profiling of Alismatis Rhizoma triterpenes in rats based on characteristic ions and a triterpene database
by: Lu Wang, et al.
Published: (2021-02-01)