Mendelian randomization reveals no associations of genetically-predicted obstructive sleep apnea with the risk of type 2 diabetes, nonalcoholic fatty liver disease, and coronary heart disease

Mendelian randomization reveals no associations of genetically-predicted obstructive sleep apnea with the risk of type 2 diabetes, nonalcoholic fatty liver disease, and coronary heart disease

BackgroundObstructive sleep apnea (OSA) has been reported to affect cardiometabolic diseases. However, whether such association is causal is still unknown. Here, we attempt to explore the effect of OSA on type 2 diabetes (T2D), nonalcoholic fatty liver disease (NAFLD) and coronary heart disease (CHD...

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Bibliographic Details
Main Authors: Xiaoxu Ding, Lanqing Zhao, Xiangguo Cui, Li Qi, Yu Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Psychiatry
Subjects:
obstructive sleep apnea
type 2 diabetes
cardiometabolic diseases
Mendelian randomization
causal inference
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1068756/full

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