Efficacy of Edible Bird’s Nest on Cognitive Functions in Experimental Animal Models: A Systematic Review
Edible bird’s nest (EBN) is constructed from saliva of swiftlets birds and consumed largely by Southeast and East Asians for its nutritional value and anti-aging properties. Although the neuroprotection of EBN in animals has been reported, there has not been yet systemically summarized. Thus, this r...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-03-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/13/3/1028 |
| _version_ | 1797540387710042112 |
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| author | Maznah Ismail Abdulsamad Alsalahi Musheer Abdulwahid Aljaberi Ramlah Mohamad Ibrahim Faizah Abu Bakar Aini Ideris |
| author_facet | Maznah Ismail Abdulsamad Alsalahi Musheer Abdulwahid Aljaberi Ramlah Mohamad Ibrahim Faizah Abu Bakar Aini Ideris |
| author_sort | Maznah Ismail |
| collection | DOAJ |
| description | Edible bird’s nest (EBN) is constructed from saliva of swiftlets birds and consumed largely by Southeast and East Asians for its nutritional value and anti-aging properties. Although the neuroprotection of EBN in animals has been reported, there has not been yet systemically summarized. Thus, this review systemically outlined the evidence of the neuroprotective activity of EBN in modulating the cognitive functions of either healthy or with induced-cognitive dysfunction animals as compared to placebos. The related records from 2010 to 2020 were retrieved from PubMed, Scopus, Web of Science and ScienceDirect using pre-specified keywords. The relevant records to the effect of EBN on cognition were selected according to the eligibility criteria and these studies underwent appraisal for the risk of bias. EBN improved the cognitive functions of induced-cognitive dysfunction and enhanced the cognitive performance of healthy animals as well as attenuated the neuroinflammations and neuro-oxidative stress in the hippocampus of these animals. Malaysian EBN could improve the cognitive functions of experimental animals as a treatment in induced cognitive dysfunction, a nutritional cognitive-enhancing agent in offspring and a prophylactic conservative effect on cognition against exposure to subsequent noxious cerebral accidents in a dose-depended manner through attenuating neuroinflammation and neuro-oxidative stress. This systemic review did not proceed meta-analysis. |
| first_indexed | 2024-03-10T13:00:25Z |
| format | Article |
| id | doaj.art-d5e2b0d4740e4caf969063522dd17036 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T13:00:25Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-d5e2b0d4740e4caf969063522dd170362023-11-21T11:36:37ZengMDPI AGNutrients2072-66432021-03-01133102810.3390/nu13031028Efficacy of Edible Bird’s Nest on Cognitive Functions in Experimental Animal Models: A Systematic ReviewMaznah Ismail0Abdulsamad Alsalahi1Musheer Abdulwahid Aljaberi2Ramlah Mohamad Ibrahim3Faizah Abu Bakar4Aini Ideris5Laboratory of Natural Medicines and Products, Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400 UPM, Selangor, MalaysiaDepartment of Pharmacology, Faculty of Pharmacy, Sana’a University, Mazbah District, Sana’a 1247, YemenDepartment of Community Health, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, Serdang 43400 UPM, Selangor, MalaysiaLaboratory of Natural Medicines and Products, Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400 UPM, Selangor, MalaysiaUZMA Clinic, Kelana Mall, SS6/12 Road, SS 6, Petaling Jaya 47301, Selangor, MalaysiaDepartment of Veterinary Clinical Studies, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Serdang 43400 UPM, Selangor, MalaysiaEdible bird’s nest (EBN) is constructed from saliva of swiftlets birds and consumed largely by Southeast and East Asians for its nutritional value and anti-aging properties. Although the neuroprotection of EBN in animals has been reported, there has not been yet systemically summarized. Thus, this review systemically outlined the evidence of the neuroprotective activity of EBN in modulating the cognitive functions of either healthy or with induced-cognitive dysfunction animals as compared to placebos. The related records from 2010 to 2020 were retrieved from PubMed, Scopus, Web of Science and ScienceDirect using pre-specified keywords. The relevant records to the effect of EBN on cognition were selected according to the eligibility criteria and these studies underwent appraisal for the risk of bias. EBN improved the cognitive functions of induced-cognitive dysfunction and enhanced the cognitive performance of healthy animals as well as attenuated the neuroinflammations and neuro-oxidative stress in the hippocampus of these animals. Malaysian EBN could improve the cognitive functions of experimental animals as a treatment in induced cognitive dysfunction, a nutritional cognitive-enhancing agent in offspring and a prophylactic conservative effect on cognition against exposure to subsequent noxious cerebral accidents in a dose-depended manner through attenuating neuroinflammation and neuro-oxidative stress. This systemic review did not proceed meta-analysis.https://www.mdpi.com/2072-6643/13/3/1028cognitionneurodegenerationneuroprotectionedible birds’ nestsystematic review |
| spellingShingle | Maznah Ismail Abdulsamad Alsalahi Musheer Abdulwahid Aljaberi Ramlah Mohamad Ibrahim Faizah Abu Bakar Aini Ideris Efficacy of Edible Bird’s Nest on Cognitive Functions in Experimental Animal Models: A Systematic Review Nutrients cognition neurodegeneration neuroprotection edible birds’ nest systematic review |
| title | Efficacy of Edible Bird’s Nest on Cognitive Functions in Experimental Animal Models: A Systematic Review |
| title_full | Efficacy of Edible Bird’s Nest on Cognitive Functions in Experimental Animal Models: A Systematic Review |
| title_fullStr | Efficacy of Edible Bird’s Nest on Cognitive Functions in Experimental Animal Models: A Systematic Review |
| title_full_unstemmed | Efficacy of Edible Bird’s Nest on Cognitive Functions in Experimental Animal Models: A Systematic Review |
| title_short | Efficacy of Edible Bird’s Nest on Cognitive Functions in Experimental Animal Models: A Systematic Review |
| title_sort | efficacy of edible bird s nest on cognitive functions in experimental animal models a systematic review |
| topic | cognition neurodegeneration neuroprotection edible birds’ nest systematic review |
| url | https://www.mdpi.com/2072-6643/13/3/1028 |
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