An Introduction to Tissue Engineering and Orthopedic Applications

Nowadays, orthopedic-related pathologic conditions are considered as a growing concern. Also, the conventional treatments (grafting techniques) are not efficacious enough for the growing clinical needs. In the last decades, researches have been focused on finding more effective alternative treatment...

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Main Authors: Fatemeh Baghaie Nia, Fatemeh Khavari, Masoumeh Firouzi, Mohammad Hossein Nabian
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2020-11-01
Series:Journal of Orthopedic and Spine Trauma
Subjects:
Online Access:https://jost.tums.ac.ir/index.php/jost/article/view/200
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author Fatemeh Baghaie Nia
Fatemeh Khavari
Masoumeh Firouzi
Mohammad Hossein Nabian
author_facet Fatemeh Baghaie Nia
Fatemeh Khavari
Masoumeh Firouzi
Mohammad Hossein Nabian
author_sort Fatemeh Baghaie Nia
collection DOAJ
description Nowadays, orthopedic-related pathologic conditions are considered as a growing concern. Also, the conventional treatments (grafting techniques) are not efficacious enough for the growing clinical needs. In the last decades, researches have been focused on finding more effective alternative treatments. Tissue engineering (TE) is a newly emerging field of science that has great potential to reduce these clinical issues. There are three main components in TE including cells, biomaterials, and signals. Choosing the best combination of these components is a vital decision in a TE process. In this review article, we are going to discuss TE and its components and also highlight some of the researches in the field of orthopedic TE by focusing on some tissues including bone, cartilage, skin, skeletal muscle, peripheral nervous system (PNS), tendon, and ligament. In the end, TE, as a new field of science, faces some major challenges that we will address some of them in this article.
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spelling doaj.art-d5e534eaabc843d0a4b83587b06856cf2022-12-21T23:51:06ZengTehran University of Medical SciencesJournal of Orthopedic and Spine Trauma2538-23302538-46002020-11-016110.18502/jost.v6i1.4534An Introduction to Tissue Engineering and Orthopedic ApplicationsFatemeh Baghaie Nia0Fatemeh Khavari1Masoumeh Firouzi2Mohammad Hossein Nabian3Department of Orthopedics, School of Medicine, Tehran University of Medical Sciences, Tehran, IranDepartment of Orthopedics, School of Medicine, Tehran University of Medical Sciences, Tehran, IranResearch Center for Neural Repair (RCNR), University of Tehran, Tehran, IranDepartment of Orthopedic Surgery, Shariati Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, IranNowadays, orthopedic-related pathologic conditions are considered as a growing concern. Also, the conventional treatments (grafting techniques) are not efficacious enough for the growing clinical needs. In the last decades, researches have been focused on finding more effective alternative treatments. Tissue engineering (TE) is a newly emerging field of science that has great potential to reduce these clinical issues. There are three main components in TE including cells, biomaterials, and signals. Choosing the best combination of these components is a vital decision in a TE process. In this review article, we are going to discuss TE and its components and also highlight some of the researches in the field of orthopedic TE by focusing on some tissues including bone, cartilage, skin, skeletal muscle, peripheral nervous system (PNS), tendon, and ligament. In the end, TE, as a new field of science, faces some major challenges that we will address some of them in this article.https://jost.tums.ac.ir/index.php/jost/article/view/200Tissue Engineering; Orthopedic; Cell Engineering; Bioengineering; Tissue Therapy
spellingShingle Fatemeh Baghaie Nia
Fatemeh Khavari
Masoumeh Firouzi
Mohammad Hossein Nabian
An Introduction to Tissue Engineering and Orthopedic Applications
Journal of Orthopedic and Spine Trauma
Tissue Engineering; Orthopedic; Cell Engineering; Bioengineering; Tissue Therapy
title An Introduction to Tissue Engineering and Orthopedic Applications
title_full An Introduction to Tissue Engineering and Orthopedic Applications
title_fullStr An Introduction to Tissue Engineering and Orthopedic Applications
title_full_unstemmed An Introduction to Tissue Engineering and Orthopedic Applications
title_short An Introduction to Tissue Engineering and Orthopedic Applications
title_sort introduction to tissue engineering and orthopedic applications
topic Tissue Engineering; Orthopedic; Cell Engineering; Bioengineering; Tissue Therapy
url https://jost.tums.ac.ir/index.php/jost/article/view/200
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