COVID-19 vaccination in people living with HIV and AIDS (PLWHA) in China: A cross-sectional study
COVID-19 appears to put people living with HIV and AIDS (PLWHA) at a higher risk of catastrophic consequences and mortality. However, investigations on the hesitancy and vaccination behavior of PLWHA in China were lacking compared to the general population. From January 2022 to March 2022, we conduc...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-01-01
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| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2022.2151798 |
| _version_ | 1797673139174375424 |
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| author | Xuan Lv Chaobo Zhao Bing Song Huihuang Huang Su Song Hai Long Weidong Liu Min Du Min Liu Jue Liu |
| author_facet | Xuan Lv Chaobo Zhao Bing Song Huihuang Huang Su Song Hai Long Weidong Liu Min Du Min Liu Jue Liu |
| author_sort | Xuan Lv |
| collection | DOAJ |
| description | COVID-19 appears to put people living with HIV and AIDS (PLWHA) at a higher risk of catastrophic consequences and mortality. However, investigations on the hesitancy and vaccination behavior of PLWHA in China were lacking compared to the general population. From January 2022 to March 2022, we conducted a multi-center cross-sectional survey of PLWHA in China. Logistic regression models were used to examine factors associated to vaccine hesitancy and COVID-19 vaccine uptake. Among 1424 participants, 108 participants (7.6%) were hesitant to be vaccinated while 1258 (88.3%) had already received at least one dose of the COVID-19 vaccine. Higher COVID-19 vaccine hesitancy was associated with older age, a lower academic level, chronic disease, lower CD4+ T cell counts, severe anxiety and despair, and high perception of illness. Lower education level, lower CD4+ T cell counts, and significant anxiety and depression were all associated with a lower vaccination rate. When compared to vaccinated participants, those who were not hesitant but nevertheless unvaccinated had a higher presence of chronic disease and lower CD4+ T cell count. Tailored interventions (e.g. targeted education programs) based on these linked characteristics were required to alleviate concerns for PLWHA in promoting COVID-19 vaccination rates, particularly for PLWHA with lower education levels, lower CD4+ T cell counts, and severe anxiety and depression. |
| first_indexed | 2024-03-11T21:40:09Z |
| format | Article |
| id | doaj.art-d5e8735086324d3290c4118a68d52a34 |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T21:40:09Z |
| publishDate | 2023-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-d5e8735086324d3290c4118a68d52a342023-09-26T13:25:46ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2023-01-0119110.1080/21645515.2022.21517982151798COVID-19 vaccination in people living with HIV and AIDS (PLWHA) in China: A cross-sectional studyXuan Lv0Chaobo Zhao1Bing Song2Huihuang Huang3Su Song4Hai Long5Weidong Liu6Min Du7Min Liu8Jue Liu9Peking UniversityPeking UniversityNational Clinical Research Center for Infectious DiseasesNational Clinical Research Center for Infectious DiseasesGuiyang Public Health Clinical CenterGuiyang Public Health Clinical CenterThe Fourth People’s Hospital of DatongPeking UniversityPeking UniversityPeking UniversityCOVID-19 appears to put people living with HIV and AIDS (PLWHA) at a higher risk of catastrophic consequences and mortality. However, investigations on the hesitancy and vaccination behavior of PLWHA in China were lacking compared to the general population. From January 2022 to March 2022, we conducted a multi-center cross-sectional survey of PLWHA in China. Logistic regression models were used to examine factors associated to vaccine hesitancy and COVID-19 vaccine uptake. Among 1424 participants, 108 participants (7.6%) were hesitant to be vaccinated while 1258 (88.3%) had already received at least one dose of the COVID-19 vaccine. Higher COVID-19 vaccine hesitancy was associated with older age, a lower academic level, chronic disease, lower CD4+ T cell counts, severe anxiety and despair, and high perception of illness. Lower education level, lower CD4+ T cell counts, and significant anxiety and depression were all associated with a lower vaccination rate. When compared to vaccinated participants, those who were not hesitant but nevertheless unvaccinated had a higher presence of chronic disease and lower CD4+ T cell count. Tailored interventions (e.g. targeted education programs) based on these linked characteristics were required to alleviate concerns for PLWHA in promoting COVID-19 vaccination rates, particularly for PLWHA with lower education levels, lower CD4+ T cell counts, and severe anxiety and depression.http://dx.doi.org/10.1080/21645515.2022.2151798covid-19hivvaccine hesitancyvaccination rate |
| spellingShingle | Xuan Lv Chaobo Zhao Bing Song Huihuang Huang Su Song Hai Long Weidong Liu Min Du Min Liu Jue Liu COVID-19 vaccination in people living with HIV and AIDS (PLWHA) in China: A cross-sectional study Human Vaccines & Immunotherapeutics covid-19 hiv vaccine hesitancy vaccination rate |
| title | COVID-19 vaccination in people living with HIV and AIDS (PLWHA) in China: A cross-sectional study |
| title_full | COVID-19 vaccination in people living with HIV and AIDS (PLWHA) in China: A cross-sectional study |
| title_fullStr | COVID-19 vaccination in people living with HIV and AIDS (PLWHA) in China: A cross-sectional study |
| title_full_unstemmed | COVID-19 vaccination in people living with HIV and AIDS (PLWHA) in China: A cross-sectional study |
| title_short | COVID-19 vaccination in people living with HIV and AIDS (PLWHA) in China: A cross-sectional study |
| title_sort | covid 19 vaccination in people living with hiv and aids plwha in china a cross sectional study |
| topic | covid-19 hiv vaccine hesitancy vaccination rate |
| url | http://dx.doi.org/10.1080/21645515.2022.2151798 |
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