Q Fever Outbreak in Industrial Setting

An outbreak of Q fever occurred in South Wales, United Kingdom, from July 15 through September 30, 2002. To investigate the outbreak a cohort and nested case-control study of persons who had worked at a cardboard manufacturing plant was conducted. The cohort included 282 employees and subcontractors...

Full description

Bibliographic Details
Main Authors: Hugo C. van Woerden, Brendan W. Mason, Lika K. Nehaul, Robert Smith, Roland L. Salmon, Brendan Healy, Manoj Valappil, Diana Westmoreland, Sarah de Martin, Meirion R. Evans, Graham Lloyd, Marysia Hamilton-Kirkwood, Nina S. Williams
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2004-07-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/10/7/03-0536_article
Description
Summary:An outbreak of Q fever occurred in South Wales, United Kingdom, from July 15 through September 30, 2002. To investigate the outbreak a cohort and nested case-control study of persons who had worked at a cardboard manufacturing plant was conducted. The cohort included 282 employees and subcontractors, of whom 253 (90%) provided blood samples and 214 (76%) completed questionnaires. Ninety-five cases of acute Q fever were identified. The epidemic curve and other data suggested an outbreak source likely occurred August 5–9, 2002. Employees in the factory’s offices were at greatest risk for infection (odds ratio 3.46; 95% confidence interval 1.38–9.06). The offices were undergoing renovation work around the time of likely exposure and contained straw board that had repeatedly been drilled. The outbreak may have been caused by aerosolization of Coxiella burnetii spore-like forms during drilling into contaminated straw board.
ISSN:1080-6040
1080-6059