Novel Anti-Melanoma Compounds Are Efficacious in A375 Cell Line Xenograft Melanoma Model in Nude Mice

Novel Anti-Melanoma Compounds Are Efficacious in A375 Cell Line Xenograft Melanoma Model in Nude Mice

Despite the successes of immunotherapy, melanoma remains one of the deadliest cancers, therefore, the need for innovation remains high. We previously reported anti-melanoma compounds that work by downregulating spliceosomal proteins hnRNPH1 and H2. In a separate study, we reported that these compoun...

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Bibliographic Details
Main Authors:	Sadeeshkumar Velayutham, Ryan Seerattan, Maab Sultan, Trisha Seal, Samaya Danthurthy, Baskaran Chinnappan, Jessica Landi, Kaitlyn Pearl, Aveta Singh, Keiran S. M. Smalley, Julia Zaias, Jun Yong Choi, Dmitriy Minond
Format:	Article
Language:	English
Published:	MDPI AG 2023-08-01
Series:	Biomolecules
Subjects:	melanoma drug discovery spliceosomal inhibition BRAF cell line xenograft organ histopathology
Online Access:	https://www.mdpi.com/2218-273X/13/9/1276

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