An adherence trilogy is essential for long-term HAART success

Adherence is the milestone of a successful therapy. Over the last decade several authors have addressed the importance of adherence for optimal results of antiretroviral (ARV) therapy. Many health care systems are investing substantial resources to make available contemporary antiretroviral therapy....

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Main Authors: Garcia Rosa, Schooley Robert T., Badaró Roberto
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Brazilian Journal of Infectious Diseases
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000500005
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author Garcia Rosa
Schooley Robert T.
Badaró Roberto
author_facet Garcia Rosa
Schooley Robert T.
Badaró Roberto
author_sort Garcia Rosa
collection DOAJ
description Adherence is the milestone of a successful therapy. Over the last decade several authors have addressed the importance of adherence for optimal results of antiretroviral (ARV) therapy. Many health care systems are investing substantial resources to make available contemporary antiretroviral therapy. Despite the large investment in medications, insufficient investments have been made into an integrated adherence component to maximize the impact of these medications. Adherence, unlike drug therapy, cannot be defined as a single method with a defined prescription or formula. Instead, it is the result of a complex interaction between the patient, a prescribed medication and the health system. Many reports are available analyzing each of these components. We have found that critical elements of adherence include the patient's knowledge about the disease and how medications will help achieve a longer and healthier life, together with the motivation to adapt to a new style of life. A trilogy composed of information, motivation and behavioral skills is essential to achieve the maximum desired level of adherence. We have computerized this trilogy in a software program for self-administration in which each of the three components is provided to the patient as many times as necessary to transmit an understanding of the problem and to help make a rational decision to adhere to the ARV treatment program. In this review we analyze several efforts and techniques to improve adherence to any recommended medication that may interfere with the patient's lifestyle and outline how the adherence trilogy can be best used to optimize the ability of ARV therapy to durably suppress plasma HIV RNA to undetectable levels.
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spelling doaj.art-d5f1c1e6d09847178ae72a4bf918402c2022-12-21T19:18:16ZengElsevierBrazilian Journal of Infectious Diseases1413-86701678-43912003-01-0175307314An adherence trilogy is essential for long-term HAART successGarcia RosaSchooley Robert T.Badaró RobertoAdherence is the milestone of a successful therapy. Over the last decade several authors have addressed the importance of adherence for optimal results of antiretroviral (ARV) therapy. Many health care systems are investing substantial resources to make available contemporary antiretroviral therapy. Despite the large investment in medications, insufficient investments have been made into an integrated adherence component to maximize the impact of these medications. Adherence, unlike drug therapy, cannot be defined as a single method with a defined prescription or formula. Instead, it is the result of a complex interaction between the patient, a prescribed medication and the health system. Many reports are available analyzing each of these components. We have found that critical elements of adherence include the patient's knowledge about the disease and how medications will help achieve a longer and healthier life, together with the motivation to adapt to a new style of life. A trilogy composed of information, motivation and behavioral skills is essential to achieve the maximum desired level of adherence. We have computerized this trilogy in a software program for self-administration in which each of the three components is provided to the patient as many times as necessary to transmit an understanding of the problem and to help make a rational decision to adhere to the ARV treatment program. In this review we analyze several efforts and techniques to improve adherence to any recommended medication that may interfere with the patient's lifestyle and outline how the adherence trilogy can be best used to optimize the ability of ARV therapy to durably suppress plasma HIV RNA to undetectable levels.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000500005Adherencecomplianceantiretroviral therapy
spellingShingle Garcia Rosa
Schooley Robert T.
Badaró Roberto
An adherence trilogy is essential for long-term HAART success
Brazilian Journal of Infectious Diseases
Adherence
compliance
antiretroviral therapy
title An adherence trilogy is essential for long-term HAART success
title_full An adherence trilogy is essential for long-term HAART success
title_fullStr An adherence trilogy is essential for long-term HAART success
title_full_unstemmed An adherence trilogy is essential for long-term HAART success
title_short An adherence trilogy is essential for long-term HAART success
title_sort adherence trilogy is essential for long term haart success
topic Adherence
compliance
antiretroviral therapy
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000500005
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