The zebrafish orthologue of the human hepatocerebral disease gene MPV17 plays pleiotropic roles in mitochondria

The zebrafish orthologue of the human hepatocerebral disease gene MPV17 plays pleiotropic roles in mitochondria

Mitochondrial DNA depletion syndromes (MDS) are a group of rare autosomal recessive disorders with early onset and no cure available. MDS are caused by mutations in nuclear genes involved in mitochondrial DNA (mtDNA) maintenance, and characterized by both a strong reduction in mtDNA content and seve...

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Bibliográfalaš dieđut
Váldodahkkit: Laura Martorano, Margherita Peron, Claudio Laquatra, Elisa Lidron, Nicola Facchinello, Giacomo Meneghetti, Natascia Tiso, Andrea Rasola, Daniele Ghezzi, Francesco Argenton
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: The Company of Biologists 2019-03-01
Ráidu:Disease Models & Mechanisms
Fáttát:
Dihydroorotate dehydrogenase
Iridophore
Mitochondrial DNA depletion syndrome
Pyrimidine
Vitamin B13
Liŋkkat:http://dmm.biologists.org/content/12/3/dmm037226

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http://dmm.biologists.org/content/12/3/dmm037226

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