Sex differences in the relationship between depression and cardiovascular disease risk: a nationwide study in Korea

Objectives This study aimed to identify sex differences in the association between depression and the risk of developing cardiovascular disease (CVD). Methods A secondary analysis was conducted of data from the fifth to seventh waves (2010−2018) of the Korea National Health and Nutrition Examination...

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Main Authors: Seol-bin Kim, Ihn Sook Jeong
Format: Article
Language:English
Published: Korea Disease Control and Prevention Agency 2021-04-01
Series:Osong Public Health and Research Perspectives
Subjects:
Online Access:http://ophrp.org/upload/pdf/j-phrp-2021-12-2-08.pdf
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author Seol-bin Kim
Ihn Sook Jeong
author_facet Seol-bin Kim
Ihn Sook Jeong
author_sort Seol-bin Kim
collection DOAJ
description Objectives This study aimed to identify sex differences in the association between depression and the risk of developing cardiovascular disease (CVD). Methods A secondary analysis was conducted of data from the fifth to seventh waves (2010−2018) of the Korea National Health and Nutrition Examination Survey. The participants were adults aged 30−74 years who had no diagnosis of CVD. The CVD risk was calculated using the Framingham Risk Score algorithm. Multiple linear regression analysis was conducted to identify the association between depression and CVD risk using a complex sample design. Results The mean CVD risk was higher in males and females with current depression (14.72% vs. 6.35%, respectively) than in males without current depression (11.67% and 4.42%, respectively). Current depression showed a significant association with CVD risk after controlling for only health-related characteristics, but the significance disappeared in both males and females when demographic characteristics were additionally controlled. Conclusion The presence of depression was not associated with CVD risk regardless of sex after controlling for confounding factors. Further studies are recommended to investigate the relationship between depression and CVD risk in a larger sample of both males and females with depression.
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spelling doaj.art-d5f450178006413abac13bfececd6b072023-09-03T13:56:23ZengKorea Disease Control and Prevention AgencyOsong Public Health and Research Perspectives2210-90992210-91102021-04-0112210511410.24171/j.phrp.2021.12.2.08603Sex differences in the relationship between depression and cardiovascular disease risk: a nationwide study in KoreaSeol-bin Kim0Ihn Sook Jeong1 Busan Regional Mental Health Welfare Center, Busan, Korea College of Nursing, Pusan National University, Yangsan, KoreaObjectives This study aimed to identify sex differences in the association between depression and the risk of developing cardiovascular disease (CVD). Methods A secondary analysis was conducted of data from the fifth to seventh waves (2010−2018) of the Korea National Health and Nutrition Examination Survey. The participants were adults aged 30−74 years who had no diagnosis of CVD. The CVD risk was calculated using the Framingham Risk Score algorithm. Multiple linear regression analysis was conducted to identify the association between depression and CVD risk using a complex sample design. Results The mean CVD risk was higher in males and females with current depression (14.72% vs. 6.35%, respectively) than in males without current depression (11.67% and 4.42%, respectively). Current depression showed a significant association with CVD risk after controlling for only health-related characteristics, but the significance disappeared in both males and females when demographic characteristics were additionally controlled. Conclusion The presence of depression was not associated with CVD risk regardless of sex after controlling for confounding factors. Further studies are recommended to investigate the relationship between depression and CVD risk in a larger sample of both males and females with depression.http://ophrp.org/upload/pdf/j-phrp-2021-12-2-08.pdfcardiovascular diseasesdepressionrisksex
spellingShingle Seol-bin Kim
Ihn Sook Jeong
Sex differences in the relationship between depression and cardiovascular disease risk: a nationwide study in Korea
Osong Public Health and Research Perspectives
cardiovascular diseases
depression
risk
sex
title Sex differences in the relationship between depression and cardiovascular disease risk: a nationwide study in Korea
title_full Sex differences in the relationship between depression and cardiovascular disease risk: a nationwide study in Korea
title_fullStr Sex differences in the relationship between depression and cardiovascular disease risk: a nationwide study in Korea
title_full_unstemmed Sex differences in the relationship between depression and cardiovascular disease risk: a nationwide study in Korea
title_short Sex differences in the relationship between depression and cardiovascular disease risk: a nationwide study in Korea
title_sort sex differences in the relationship between depression and cardiovascular disease risk a nationwide study in korea
topic cardiovascular diseases
depression
risk
sex
url http://ophrp.org/upload/pdf/j-phrp-2021-12-2-08.pdf
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