Impact of connecting tuberculosis directly observed therapy short-course with smoking cessation on health-related quality of life
Background With evolving evidence of association between tuberculosis (TB) and tobacco smoking, recommendations for the inclusion of tobacco cessation interventions in TB care are becoming increasingly important and more widely disseminated. Connecting TB and tobacco cessation interventions has been...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
European Publishing
2012-02-01
|
| Series: | Tobacco Induced Diseases |
| Subjects: | |
| Online Access: | http://www.journalssystem.com/tid/Impact-of-connecting-tuberculosis-directly-observed-therapy-short-course-with-smoking-cessation-on-health-related-quality-of-life,66083,0,2.html |
| _version_ | 1811272346837712896 |
|---|---|
| author | Ahmed Awaisu Mohamad Haniki Nik Mohamed Noorliza Mohamad Noordin Abdul Razak Muttalif Noorizan Abd Aziz Syed Azhar Syed Sulaiman Aziah Ahmad Mahayiddin |
| author_facet | Ahmed Awaisu Mohamad Haniki Nik Mohamed Noorliza Mohamad Noordin Abdul Razak Muttalif Noorizan Abd Aziz Syed Azhar Syed Sulaiman Aziah Ahmad Mahayiddin |
| author_sort | Ahmed Awaisu |
| collection | DOAJ |
| description | Background
With evolving evidence of association between tuberculosis (TB) and tobacco smoking,
recommendations for the inclusion of tobacco cessation interventions in TB care are becoming increasingly
important and more widely disseminated. Connecting TB and tobacco cessation interventions has been strongly
advocated as this may yield better outcomes. However, no study has documented the impact of such connection
on health-related quality of life (HRQoL). The objective of this study was to document the impact of an integrated
TB directly observed therapy short-course (DOTS) plus smoking cessation intervention (SCI) on HRQoL.
Methods
This was a multi-centered non-randomized controlled study involving 120 TB patients who were current
smokers at the time of TB diagnosis in Malaysia. Patients were assigned to either of two groups: the usual TB-DOTS
plus SCI (SCIDOTS group) or the usual TB-DOTS only (DOTS group). The effect of the novel strategy on HRQoL was
measured using EQ-5D questionnaire. Two-way repeated measure ANOVA was used to examine the effects.
Results
When compared, participants who received the integrated intervention had a better HRQoL than those
who received the usual TB care. The SCIDOTS group had a significantly greater increase in EQ-5D utility score than
the DOTS group during 6 months follow-up (mean ± SD = 0.98 ± 0.08 vs. 0.91 ± 0.14, p = 0.006). Similarly, the
mean scores for EQ-VAS showed a consistently similar trend as the EQ-5D indices, with the scores increasing over
the course of TB treatment. Furthermore, for the EQ-VAS, there were significant main effects for group [F (1, 84) =
4.91, p = 0.029, h2 = 0.06], time [F (2, 168) = 139.50, p = < 0.001, h2 = 0.62] and group x time interaction [F (2, 168)
= 13.89, p = < 0.001, h2 = 0.14].
Conclusions
This study supports the evidence that an integrated TB-tobacco treatment strategy could potentially
improve overall quality of life outcomes among TB patients who are smokers. |
| first_indexed | 2024-04-12T22:38:38Z |
| format | Article |
| id | doaj.art-d5f508e610424730997f2629632b2540 |
| institution | Directory Open Access Journal |
| issn | 1617-9625 |
| language | English |
| last_indexed | 2024-04-12T22:38:38Z |
| publishDate | 2012-02-01 |
| publisher | European Publishing |
| record_format | Article |
| series | Tobacco Induced Diseases |
| spelling | doaj.art-d5f508e610424730997f2629632b25402022-12-22T03:13:47ZengEuropean PublishingTobacco Induced Diseases1617-96252012-02-0110February10.1186/1617-9625-10-266083Impact of connecting tuberculosis directly observed therapy short-course with smoking cessation on health-related quality of lifeAhmed Awaisu0Mohamad Haniki Nik Mohamed1Noorliza Mohamad Noordin2Abdul Razak Muttalif3Noorizan Abd Aziz4Syed Azhar Syed Sulaiman5Aziah Ahmad Mahayiddin6College of Pharmacy, Qatar University, P.O. Box 2713, Doha, QatarFaculty of Pharmacy, International Islamic University Malaysia, 25200 Kuantan, MalaysiaInstitute for Health Management, Ministry of Health, 59000 Kuala Lumpur, MalaysiaInstitute for Respiratory Medicine, 53000 Wilayah Persekutuan, Kuala Lumpur, MalaysiaFaculty of Pharmacy, Universiti Technology Mara, 5600 Puncak Alam, MalaysiaSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Penang, MalaysiaInstitute for Respiratory Medicine, 53000 Wilayah Persekutuan, Kuala Lumpur, MalaysiaBackground With evolving evidence of association between tuberculosis (TB) and tobacco smoking, recommendations for the inclusion of tobacco cessation interventions in TB care are becoming increasingly important and more widely disseminated. Connecting TB and tobacco cessation interventions has been strongly advocated as this may yield better outcomes. However, no study has documented the impact of such connection on health-related quality of life (HRQoL). The objective of this study was to document the impact of an integrated TB directly observed therapy short-course (DOTS) plus smoking cessation intervention (SCI) on HRQoL. Methods This was a multi-centered non-randomized controlled study involving 120 TB patients who were current smokers at the time of TB diagnosis in Malaysia. Patients were assigned to either of two groups: the usual TB-DOTS plus SCI (SCIDOTS group) or the usual TB-DOTS only (DOTS group). The effect of the novel strategy on HRQoL was measured using EQ-5D questionnaire. Two-way repeated measure ANOVA was used to examine the effects. Results When compared, participants who received the integrated intervention had a better HRQoL than those who received the usual TB care. The SCIDOTS group had a significantly greater increase in EQ-5D utility score than the DOTS group during 6 months follow-up (mean ± SD = 0.98 ± 0.08 vs. 0.91 ± 0.14, p = 0.006). Similarly, the mean scores for EQ-VAS showed a consistently similar trend as the EQ-5D indices, with the scores increasing over the course of TB treatment. Furthermore, for the EQ-VAS, there were significant main effects for group [F (1, 84) = 4.91, p = 0.029, h2 = 0.06], time [F (2, 168) = 139.50, p = < 0.001, h2 = 0.62] and group x time interaction [F (2, 168) = 13.89, p = < 0.001, h2 = 0.14]. Conclusions This study supports the evidence that an integrated TB-tobacco treatment strategy could potentially improve overall quality of life outcomes among TB patients who are smokers.http://www.journalssystem.com/tid/Impact-of-connecting-tuberculosis-directly-observed-therapy-short-course-with-smoking-cessation-on-health-related-quality-of-life,66083,0,2.htmldotsoutcomesQuality of Lifesmoking cessation interventiontuberculosis |
| spellingShingle | Ahmed Awaisu Mohamad Haniki Nik Mohamed Noorliza Mohamad Noordin Abdul Razak Muttalif Noorizan Abd Aziz Syed Azhar Syed Sulaiman Aziah Ahmad Mahayiddin Impact of connecting tuberculosis directly observed therapy short-course with smoking cessation on health-related quality of life Tobacco Induced Diseases dots outcomes Quality of Life smoking cessation intervention tuberculosis |
| title | Impact of connecting tuberculosis directly observed therapy short-course with smoking cessation on health-related quality of life |
| title_full | Impact of connecting tuberculosis directly observed therapy short-course with smoking cessation on health-related quality of life |
| title_fullStr | Impact of connecting tuberculosis directly observed therapy short-course with smoking cessation on health-related quality of life |
| title_full_unstemmed | Impact of connecting tuberculosis directly observed therapy short-course with smoking cessation on health-related quality of life |
| title_short | Impact of connecting tuberculosis directly observed therapy short-course with smoking cessation on health-related quality of life |
| title_sort | impact of connecting tuberculosis directly observed therapy short course with smoking cessation on health related quality of life |
| topic | dots outcomes Quality of Life smoking cessation intervention tuberculosis |
| url | http://www.journalssystem.com/tid/Impact-of-connecting-tuberculosis-directly-observed-therapy-short-course-with-smoking-cessation-on-health-related-quality-of-life,66083,0,2.html |
| work_keys_str_mv | AT ahmedawaisu impactofconnectingtuberculosisdirectlyobservedtherapyshortcoursewithsmokingcessationonhealthrelatedqualityoflife AT mohamadhanikinikmohamed impactofconnectingtuberculosisdirectlyobservedtherapyshortcoursewithsmokingcessationonhealthrelatedqualityoflife AT noorlizamohamadnoordin impactofconnectingtuberculosisdirectlyobservedtherapyshortcoursewithsmokingcessationonhealthrelatedqualityoflife AT abdulrazakmuttalif impactofconnectingtuberculosisdirectlyobservedtherapyshortcoursewithsmokingcessationonhealthrelatedqualityoflife AT noorizanabdaziz impactofconnectingtuberculosisdirectlyobservedtherapyshortcoursewithsmokingcessationonhealthrelatedqualityoflife AT syedazharsyedsulaiman impactofconnectingtuberculosisdirectlyobservedtherapyshortcoursewithsmokingcessationonhealthrelatedqualityoflife AT aziahahmadmahayiddin impactofconnectingtuberculosisdirectlyobservedtherapyshortcoursewithsmokingcessationonhealthrelatedqualityoflife |