Descriptive study of severe hospitalized cases of laboratory-confirmed influenza during five epidemic seasons (2010–2015)
Abstract Objective The Plan of Information on Acute Respiratory Infections in Catalonia (PIDIRAC) included the surveillance of severe hospitalized cases of laboratory-confirmed influenza (SHCLCI) in 2009. The objective of this study was to determine the clinical, epidemiological and virological feat...
| Main Authors: | , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2018-04-01
|
| Series: | BMC Research Notes |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13104-018-3349-y |
| _version_ | 1811262752585416704 |
|---|---|
| author | Núria Torner Ana Martínez Luca Basile MMar Mosquera Andrés Antón Cristina Rius M. Rosa Sala Sofia Minguell Elsa Plasencia Mónica Carol Pere Godoy Núria Follia Irene Barrabeig M. Angeles Marcos Tomàs Pumarola Mireia Jané |
| author_facet | Núria Torner Ana Martínez Luca Basile MMar Mosquera Andrés Antón Cristina Rius M. Rosa Sala Sofia Minguell Elsa Plasencia Mónica Carol Pere Godoy Núria Follia Irene Barrabeig M. Angeles Marcos Tomàs Pumarola Mireia Jané |
| author_sort | Núria Torner |
| collection | DOAJ |
| description | Abstract Objective The Plan of Information on Acute Respiratory Infections in Catalonia (PIDIRAC) included the surveillance of severe hospitalized cases of laboratory-confirmed influenza (SHCLCI) in 2009. The objective of this study was to determine the clinical, epidemiological and virological features of SHCLCI recorded in 12 sentinel hospitals during five influenza seasons. Results From a sample of SHCLCI recorded during the 5 influenza epidemics seasons from 2010–2011 to 2014–2015, Cases were confirmed by PCR and/or viral isolation in cell cultures from respiratory samples. A total of 1400 SHCLCI were recorded, 33% required ICU admission and 12% died. The median age of cases was 61 years (range 0–101 years); 70.5% were unvaccinated; 80.4% received antiviral treatment (in 79.6 and 24% of cases within 48 h after hospital admission and the onset of symptoms, respectively); influenza virus A [37.9% A (H1N1)pdm09, 29.3% A (H3N2)] was identified in 87.7% of cases. Surveillance of SHCLCI provides an estimate of the severity of seasonal influenza epidemics and the identification and characterization of at-risk groups in order to facilitate preventive measures such as vaccination and early antiviral treatment. |
| first_indexed | 2024-04-12T19:31:06Z |
| format | Article |
| id | doaj.art-d5f7b7f1feff497fbf6cd518dc8b7c9a |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-04-12T19:31:06Z |
| publishDate | 2018-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-d5f7b7f1feff497fbf6cd518dc8b7c9a2022-12-22T03:19:20ZengBMCBMC Research Notes1756-05002018-04-011111610.1186/s13104-018-3349-yDescriptive study of severe hospitalized cases of laboratory-confirmed influenza during five epidemic seasons (2010–2015)Núria Torner0Ana Martínez1Luca Basile2MMar Mosquera3Andrés Antón4Cristina Rius5M. Rosa Sala6Sofia Minguell7Elsa Plasencia8Mónica Carol9Pere Godoy10Núria Follia11Irene Barrabeig12M. Angeles Marcos13Tomàs Pumarola14Mireia Jané15Public Health Agency of CataloniaPublic Health Agency of CataloniaPublic Health Agency of CataloniaMicrobiology Department, Hospital Clínic de BarcelonaMicrobiology Department, Hospital Universitari Vall d’Hebron de BarcelonaCIBER Epidemiologia y Salud Pública CIBERESPPublic Health Agency of CataloniaPublic Health Agency of CataloniaPublic Health Agency of CataloniaPublic Health Agency of CataloniaPublic Health Agency of CataloniaPublic Health Agency of CataloniaPublic Health Agency of CataloniaMicrobiology Department, Hospital Clínic de BarcelonaMicrobiology Department, Hospital Universitari Vall d’Hebron de BarcelonaPublic Health Agency of CataloniaAbstract Objective The Plan of Information on Acute Respiratory Infections in Catalonia (PIDIRAC) included the surveillance of severe hospitalized cases of laboratory-confirmed influenza (SHCLCI) in 2009. The objective of this study was to determine the clinical, epidemiological and virological features of SHCLCI recorded in 12 sentinel hospitals during five influenza seasons. Results From a sample of SHCLCI recorded during the 5 influenza epidemics seasons from 2010–2011 to 2014–2015, Cases were confirmed by PCR and/or viral isolation in cell cultures from respiratory samples. A total of 1400 SHCLCI were recorded, 33% required ICU admission and 12% died. The median age of cases was 61 years (range 0–101 years); 70.5% were unvaccinated; 80.4% received antiviral treatment (in 79.6 and 24% of cases within 48 h after hospital admission and the onset of symptoms, respectively); influenza virus A [37.9% A (H1N1)pdm09, 29.3% A (H3N2)] was identified in 87.7% of cases. Surveillance of SHCLCI provides an estimate of the severity of seasonal influenza epidemics and the identification and characterization of at-risk groups in order to facilitate preventive measures such as vaccination and early antiviral treatment.http://link.springer.com/article/10.1186/s13104-018-3349-yInfluenzaSurveillanceEpidemiologyAntiviral drugsVaccine |
| spellingShingle | Núria Torner Ana Martínez Luca Basile MMar Mosquera Andrés Antón Cristina Rius M. Rosa Sala Sofia Minguell Elsa Plasencia Mónica Carol Pere Godoy Núria Follia Irene Barrabeig M. Angeles Marcos Tomàs Pumarola Mireia Jané Descriptive study of severe hospitalized cases of laboratory-confirmed influenza during five epidemic seasons (2010–2015) BMC Research Notes Influenza Surveillance Epidemiology Antiviral drugs Vaccine |
| title | Descriptive study of severe hospitalized cases of laboratory-confirmed influenza during five epidemic seasons (2010–2015) |
| title_full | Descriptive study of severe hospitalized cases of laboratory-confirmed influenza during five epidemic seasons (2010–2015) |
| title_fullStr | Descriptive study of severe hospitalized cases of laboratory-confirmed influenza during five epidemic seasons (2010–2015) |
| title_full_unstemmed | Descriptive study of severe hospitalized cases of laboratory-confirmed influenza during five epidemic seasons (2010–2015) |
| title_short | Descriptive study of severe hospitalized cases of laboratory-confirmed influenza during five epidemic seasons (2010–2015) |
| title_sort | descriptive study of severe hospitalized cases of laboratory confirmed influenza during five epidemic seasons 2010 2015 |
| topic | Influenza Surveillance Epidemiology Antiviral drugs Vaccine |
| url | http://link.springer.com/article/10.1186/s13104-018-3349-y |
| work_keys_str_mv | AT nuriatorner descriptivestudyofseverehospitalizedcasesoflaboratoryconfirmedinfluenzaduringfiveepidemicseasons20102015 AT anamartinez descriptivestudyofseverehospitalizedcasesoflaboratoryconfirmedinfluenzaduringfiveepidemicseasons20102015 AT lucabasile descriptivestudyofseverehospitalizedcasesoflaboratoryconfirmedinfluenzaduringfiveepidemicseasons20102015 AT mmarmosquera descriptivestudyofseverehospitalizedcasesoflaboratoryconfirmedinfluenzaduringfiveepidemicseasons20102015 AT andresanton descriptivestudyofseverehospitalizedcasesoflaboratoryconfirmedinfluenzaduringfiveepidemicseasons20102015 AT cristinarius descriptivestudyofseverehospitalizedcasesoflaboratoryconfirmedinfluenzaduringfiveepidemicseasons20102015 AT mrosasala descriptivestudyofseverehospitalizedcasesoflaboratoryconfirmedinfluenzaduringfiveepidemicseasons20102015 AT sofiaminguell descriptivestudyofseverehospitalizedcasesoflaboratoryconfirmedinfluenzaduringfiveepidemicseasons20102015 AT elsaplasencia descriptivestudyofseverehospitalizedcasesoflaboratoryconfirmedinfluenzaduringfiveepidemicseasons20102015 AT monicacarol descriptivestudyofseverehospitalizedcasesoflaboratoryconfirmedinfluenzaduringfiveepidemicseasons20102015 AT peregodoy descriptivestudyofseverehospitalizedcasesoflaboratoryconfirmedinfluenzaduringfiveepidemicseasons20102015 AT nuriafollia descriptivestudyofseverehospitalizedcasesoflaboratoryconfirmedinfluenzaduringfiveepidemicseasons20102015 AT irenebarrabeig descriptivestudyofseverehospitalizedcasesoflaboratoryconfirmedinfluenzaduringfiveepidemicseasons20102015 AT mangelesmarcos descriptivestudyofseverehospitalizedcasesoflaboratoryconfirmedinfluenzaduringfiveepidemicseasons20102015 AT tomaspumarola descriptivestudyofseverehospitalizedcasesoflaboratoryconfirmedinfluenzaduringfiveepidemicseasons20102015 AT mireiajane descriptivestudyofseverehospitalizedcasesoflaboratoryconfirmedinfluenzaduringfiveepidemicseasons20102015 |