Presenting artificial intelligence, deep learning, and machine learning studies to clinicians and healthcare stakeholders: an introductory reference with a guideline and a Clinical AI Research (CAIR) checklist proposal

Background and purpose — Artificial intelligence (AI), deep learning (DL), and machine learning (ML) have become common research fields in orthopedics and medicine in general. Engineers perform much of the work. While they gear the results towards healthcare professionals, the difference in competen...

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Main Authors: Jakub Olczak, John Pavlopoulos, Jasper Prijs, Frank F A Ijpma, Job N Doornberg, Claes Lundström, Joel Hedlund, Max Gordon
Format: Article
Language:English
Published: Medical Journals Sweden 2021-10-01
Series:Acta Orthopaedica
Online Access:http://dx.doi.org/10.1080/17453674.2021.1918389
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author Jakub Olczak
John Pavlopoulos
Jasper Prijs
Frank F A Ijpma
Job N Doornberg
Claes Lundström
Joel Hedlund
Max Gordon
author_facet Jakub Olczak
John Pavlopoulos
Jasper Prijs
Frank F A Ijpma
Job N Doornberg
Claes Lundström
Joel Hedlund
Max Gordon
author_sort Jakub Olczak
collection DOAJ
description Background and purpose — Artificial intelligence (AI), deep learning (DL), and machine learning (ML) have become common research fields in orthopedics and medicine in general. Engineers perform much of the work. While they gear the results towards healthcare professionals, the difference in competencies and goals creates challenges for collaboration and knowledge exchange. We aim to provide clinicians with a context and understanding of AI research by facilitating communication between creators, researchers, clinicians, and readers of medical AI and ML research. Methods and results — We present the common tasks, considerations, and pitfalls (both methodological and ethical) that clinicians will encounter in AI research. We discuss the following topics: labeling, missing data, training, testing, and overfitting. Common performance and outcome measures for various AI and ML tasks are presented, including accuracy, precision, recall, F1 score, Dice score, the area under the curve, and ROC curves. We also discuss ethical considerations in terms of privacy, fairness, autonomy, safety, responsibility, and liability regarding data collecting or sharing. Interpretation — We have developed guidelines for reporting medical AI research to clinicians in the run-up to a broader consensus process. The proposed guidelines consist of a Clinical Artificial Intelligence Research (CAIR) checklist and specific performance metrics guidelines to present and evaluate research using AI components. Researchers, engineers, clinicians, and other stakeholders can use these proposal guidelines and the CAIR checklist to read, present, and evaluate AI research geared towards a healthcare setting.
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spelling doaj.art-d5f89633677b492791e7c073220f9c522022-12-21T17:23:33ZengMedical Journals SwedenActa Orthopaedica1745-36741745-36822021-10-0192551352510.1080/17453674.2021.19183891918389Presenting artificial intelligence, deep learning, and machine learning studies to clinicians and healthcare stakeholders: an introductory reference with a guideline and a Clinical AI Research (CAIR) checklist proposalJakub Olczak0John Pavlopoulos1Jasper Prijs2Frank F A Ijpma3Job N Doornberg4Claes Lundström5Joel Hedlund6Max Gordon7Institute of Clinical Sciences, Danderyd University Hospital, Karolinska InstituteDepartment of Computer and System Sciences, Stockholm UniversityFlinders UniversityDepartment of Trauma Surgery, University Medical Center Groningen, University of GroningenFlinders UniversityCenter for Medical Image Science and Visualization, Linköping UniversityCenter for Medical Image Science and Visualization, Linköping UniversityInstitute of Clinical Sciences, Danderyd University Hospital, Karolinska InstituteBackground and purpose — Artificial intelligence (AI), deep learning (DL), and machine learning (ML) have become common research fields in orthopedics and medicine in general. Engineers perform much of the work. While they gear the results towards healthcare professionals, the difference in competencies and goals creates challenges for collaboration and knowledge exchange. We aim to provide clinicians with a context and understanding of AI research by facilitating communication between creators, researchers, clinicians, and readers of medical AI and ML research. Methods and results — We present the common tasks, considerations, and pitfalls (both methodological and ethical) that clinicians will encounter in AI research. We discuss the following topics: labeling, missing data, training, testing, and overfitting. Common performance and outcome measures for various AI and ML tasks are presented, including accuracy, precision, recall, F1 score, Dice score, the area under the curve, and ROC curves. We also discuss ethical considerations in terms of privacy, fairness, autonomy, safety, responsibility, and liability regarding data collecting or sharing. Interpretation — We have developed guidelines for reporting medical AI research to clinicians in the run-up to a broader consensus process. The proposed guidelines consist of a Clinical Artificial Intelligence Research (CAIR) checklist and specific performance metrics guidelines to present and evaluate research using AI components. Researchers, engineers, clinicians, and other stakeholders can use these proposal guidelines and the CAIR checklist to read, present, and evaluate AI research geared towards a healthcare setting.http://dx.doi.org/10.1080/17453674.2021.1918389
spellingShingle Jakub Olczak
John Pavlopoulos
Jasper Prijs
Frank F A Ijpma
Job N Doornberg
Claes Lundström
Joel Hedlund
Max Gordon
Presenting artificial intelligence, deep learning, and machine learning studies to clinicians and healthcare stakeholders: an introductory reference with a guideline and a Clinical AI Research (CAIR) checklist proposal
Acta Orthopaedica
title Presenting artificial intelligence, deep learning, and machine learning studies to clinicians and healthcare stakeholders: an introductory reference with a guideline and a Clinical AI Research (CAIR) checklist proposal
title_full Presenting artificial intelligence, deep learning, and machine learning studies to clinicians and healthcare stakeholders: an introductory reference with a guideline and a Clinical AI Research (CAIR) checklist proposal
title_fullStr Presenting artificial intelligence, deep learning, and machine learning studies to clinicians and healthcare stakeholders: an introductory reference with a guideline and a Clinical AI Research (CAIR) checklist proposal
title_full_unstemmed Presenting artificial intelligence, deep learning, and machine learning studies to clinicians and healthcare stakeholders: an introductory reference with a guideline and a Clinical AI Research (CAIR) checklist proposal
title_short Presenting artificial intelligence, deep learning, and machine learning studies to clinicians and healthcare stakeholders: an introductory reference with a guideline and a Clinical AI Research (CAIR) checklist proposal
title_sort presenting artificial intelligence deep learning and machine learning studies to clinicians and healthcare stakeholders an introductory reference with a guideline and a clinical ai research cair checklist proposal
url http://dx.doi.org/10.1080/17453674.2021.1918389
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