Baseline Sequencing Surveillance of Public Clinical Testing, Hospitals, and Community Wastewater Reveals Rapid Emergence of SARS-CoV-2 Omicron Variant of Concern in Arizona, USA

Baseline Sequencing Surveillance of Public Clinical Testing, Hospitals, and Community Wastewater Reveals Rapid Emergence of SARS-CoV-2 Omicron Variant of Concern in Arizona, USA

ABSTRACT The adaptive evolution of SARS-CoV-2 variants is driven by selection for increased viral fitness in transmissibility and immune evasion. Understanding the dynamics of how an emergent variant sweeps across populations can better inform public health response preparedness for future variants....

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Bibliographic Details
Main Authors: Matthew F. Smith, Steven C. Holland, Mihyun B. Lee, James C. Hu, Nghia C. Pham, Regan A. Sullins, LaRinda A. Holland, Tianchen Mu, Alexis W. Thomas, Remington Fitch, Erin M. Driver, Rolf U. Halden, Michelle Villegas-Gold, Sheri Sanders, Jennifer L. Krauss, Lora Nordstrom, Mary Mulrow, Michael White, Vel Murugan, Efrem S. Lim
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:mBio
Subjects:
emergence dynamics
hospital-associated mutations
Omicron variant
SARS-CoV-2
wastewater surveillance
Online Access:https://journals.asm.org/doi/10.1128/mbio.03101-22

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