QUALITY OF LIFE AND ITS DYNAMICS IN PATIENTS WITH ATRIAL FIBRILLATION AFTER LEAVING THE INTERNATIONAL CLINICAL TRIAL
<p>Aim. To study changes in quality of life (QoL) in patients with atrial fibrillation (AF) treated with warfarin after leaving the international clinical trial. Material and Methods. Patients with AF who were managed at cardiology department of the University Hospital participated in the stud...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Столичная издательская компания
2015-12-01
|
| Series: | Рациональная фармакотерапия в кардиологии |
| Subjects: | |
| Online Access: | http://www.rpcardio.ru/jour/article/view/532 |
| _version_ | 1797762012197945344 |
|---|---|
| author | E. L. Artanova L. E. Kon'shina I. M. Sokolov Y. G. Shvarts |
| author_facet | E. L. Artanova L. E. Kon'shina I. M. Sokolov Y. G. Shvarts |
| author_sort | E. L. Artanova |
| collection | DOAJ |
| description | <p>Aim. To study changes in quality of life (QoL) in patients with atrial fibrillation (AF) treated with warfarin after leaving the international clinical trial. Material and Methods. Patients with AF who were managed at cardiology department of the University Hospital participated in the study. Patients of the main group (n=79) completed the international clinical trial with warfarin titration to therapeutic doses and subsequent therapy monitoring at least 1 year . Patients of the control group (n=23) had never taken part in clinical trials. QoL was evaluated with the 36-Item Short-Form Health Survey (SF 36) questionnaire after international clinical trial living or hospital discharge (initially) and in 3, 6 months of follow-up in outpatient clinic. Results. The most significant changes were observed in the first 3 months. In patients of the main group after clinical trial leaving physical component of QoL decreased from 65 (52.0-77.0) to 52 (25.0–55.0) points (p<0.05) and emotional component – from 65 (55.0-70.0) to 60 (50.0–65.0) points (p<0.05). At the same period opposite dynamics was observed in patients of the control group after hospital discharge. Physical component of QoL increased from 55 (25.0-65.0) to 65 (52.0–77.0) points (p<0.05) and emotional component - from 60 (47.5- 65.0) to 70 (60.0–75.0) points (p<0.05). In the next 3 months QoL levels have not changed significantly in patients of the both groups. Conclusion. International clinical trial living affects QoL in patients with AF . The physical component of QoL worsens most significantly.</p> |
| first_indexed | 2024-03-12T19:21:17Z |
| format | Article |
| id | doaj.art-d5fb019558904aabbde41add8d40b64b |
| institution | Directory Open Access Journal |
| issn | 1819-6446 2225-3653 |
| language | English |
| last_indexed | 2024-03-12T19:21:17Z |
| publishDate | 2015-12-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj.art-d5fb019558904aabbde41add8d40b64b2023-08-02T05:09:02ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-12-018215415710.1234/1819-6446-2012-2-154-157532QUALITY OF LIFE AND ITS DYNAMICS IN PATIENTS WITH ATRIAL FIBRILLATION AFTER LEAVING THE INTERNATIONAL CLINICAL TRIALE. L. Artanova0L. E. Kon'shina1I. M. Sokolov2Y. G. Shvarts3Саратовский государственный медицинский университет им. В.И. РазумовскогоСаратовский государственный медицинский университет им. В.И. РазумовскогоСаратовский государственный медицинский университет им. В.И. РазумовскогоСаратовский государственный медицинский университет им. В.И. Разумовского<p>Aim. To study changes in quality of life (QoL) in patients with atrial fibrillation (AF) treated with warfarin after leaving the international clinical trial. Material and Methods. Patients with AF who were managed at cardiology department of the University Hospital participated in the study. Patients of the main group (n=79) completed the international clinical trial with warfarin titration to therapeutic doses and subsequent therapy monitoring at least 1 year . Patients of the control group (n=23) had never taken part in clinical trials. QoL was evaluated with the 36-Item Short-Form Health Survey (SF 36) questionnaire after international clinical trial living or hospital discharge (initially) and in 3, 6 months of follow-up in outpatient clinic. Results. The most significant changes were observed in the first 3 months. In patients of the main group after clinical trial leaving physical component of QoL decreased from 65 (52.0-77.0) to 52 (25.0–55.0) points (p<0.05) and emotional component – from 65 (55.0-70.0) to 60 (50.0–65.0) points (p<0.05). At the same period opposite dynamics was observed in patients of the control group after hospital discharge. Physical component of QoL increased from 55 (25.0-65.0) to 65 (52.0–77.0) points (p<0.05) and emotional component - from 60 (47.5- 65.0) to 70 (60.0–75.0) points (p<0.05). In the next 3 months QoL levels have not changed significantly in patients of the both groups. Conclusion. International clinical trial living affects QoL in patients with AF . The physical component of QoL worsens most significantly.</p>http://www.rpcardio.ru/jour/article/view/532фибрилляция предсердийкачество жизниклинические исследованияварфарин |
| spellingShingle | E. L. Artanova L. E. Kon'shina I. M. Sokolov Y. G. Shvarts QUALITY OF LIFE AND ITS DYNAMICS IN PATIENTS WITH ATRIAL FIBRILLATION AFTER LEAVING THE INTERNATIONAL CLINICAL TRIAL Рациональная фармакотерапия в кардиологии фибрилляция предсердий качество жизни клинические исследования варфарин |
| title | QUALITY OF LIFE AND ITS DYNAMICS IN PATIENTS WITH ATRIAL FIBRILLATION AFTER LEAVING THE INTERNATIONAL CLINICAL TRIAL |
| title_full | QUALITY OF LIFE AND ITS DYNAMICS IN PATIENTS WITH ATRIAL FIBRILLATION AFTER LEAVING THE INTERNATIONAL CLINICAL TRIAL |
| title_fullStr | QUALITY OF LIFE AND ITS DYNAMICS IN PATIENTS WITH ATRIAL FIBRILLATION AFTER LEAVING THE INTERNATIONAL CLINICAL TRIAL |
| title_full_unstemmed | QUALITY OF LIFE AND ITS DYNAMICS IN PATIENTS WITH ATRIAL FIBRILLATION AFTER LEAVING THE INTERNATIONAL CLINICAL TRIAL |
| title_short | QUALITY OF LIFE AND ITS DYNAMICS IN PATIENTS WITH ATRIAL FIBRILLATION AFTER LEAVING THE INTERNATIONAL CLINICAL TRIAL |
| title_sort | quality of life and its dynamics in patients with atrial fibrillation after leaving the international clinical trial |
| topic | фибрилляция предсердий качество жизни клинические исследования варфарин |
| url | http://www.rpcardio.ru/jour/article/view/532 |
| work_keys_str_mv | AT elartanova qualityoflifeanditsdynamicsinpatientswithatrialfibrillationafterleavingtheinternationalclinicaltrial AT lekonshina qualityoflifeanditsdynamicsinpatientswithatrialfibrillationafterleavingtheinternationalclinicaltrial AT imsokolov qualityoflifeanditsdynamicsinpatientswithatrialfibrillationafterleavingtheinternationalclinicaltrial AT ygshvarts qualityoflifeanditsdynamicsinpatientswithatrialfibrillationafterleavingtheinternationalclinicaltrial |