Case example of a jail-based cancer prevention clinical trial: Social determinants of health framework, novel experimental design, and retention strategies to facilitate long-term follow-up of clinical trial participants
Clinical trials conducted with incarcerated populations are rare. We present a case example of one such jail-based cancer prevention clinical trial to demonstrate the importance of including a theory-driven approach to intervention framing, novel experimental designs to boost access to low-risk tria...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Cambridge University Press
2023-01-01
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| Series: | Journal of Clinical and Translational Science |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2059866123005617/type/journal_article |
| _version_ | 1797754751378522112 |
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| author | Pablo Kennedy Rubina Ratnaparkhi Jaehoon Lee Jason E. Glenn Patricia J. Kelly Kim S. Kimminau Stephanie Assimonye Megha Ramaswamy |
| author_facet | Pablo Kennedy Rubina Ratnaparkhi Jaehoon Lee Jason E. Glenn Patricia J. Kelly Kim S. Kimminau Stephanie Assimonye Megha Ramaswamy |
| author_sort | Pablo Kennedy |
| collection | DOAJ |
| description | Clinical trials conducted with incarcerated populations are rare. We present a case example of one such jail-based cancer prevention clinical trial to demonstrate the importance of including a theory-driven approach to intervention framing, novel experimental designs to boost access to low-risk trials, and retention strategies for long-term follow-up of hard-to-reach populations. As such we offer a social determinant of health framework to ensure cancer prevention research is conducted through the lenses of health promotion and health equity. Deviations from the gold-standard randomized control design, transparent systematic allotment, and street-based outreach retention strategies contribute to the feasibility of conducting clinical trials in carceral settings and after people leave jail. Best practices presented can be used in design and conduct of future clinical trials with criminal legal system-involved populations. |
| first_indexed | 2024-03-12T17:37:07Z |
| format | Article |
| id | doaj.art-d5fb76b047c8430d8f17a26d9d460282 |
| institution | Directory Open Access Journal |
| issn | 2059-8661 |
| language | English |
| last_indexed | 2024-03-12T17:37:07Z |
| publishDate | 2023-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Journal of Clinical and Translational Science |
| spelling | doaj.art-d5fb76b047c8430d8f17a26d9d4602822023-08-04T10:15:58ZengCambridge University PressJournal of Clinical and Translational Science2059-86612023-01-01710.1017/cts.2023.561Case example of a jail-based cancer prevention clinical trial: Social determinants of health framework, novel experimental design, and retention strategies to facilitate long-term follow-up of clinical trial participantsPablo Kennedy0https://orcid.org/0000-0002-2795-6446Rubina Ratnaparkhi1Jaehoon Lee2Jason E. Glenn3Patricia J. Kelly4https://orcid.org/0000-0002-8143-7153Kim S. Kimminau5https://orcid.org/0000-0002-2252-7941Stephanie Assimonye6Megha Ramaswamy7University of Kansas School of Medicine, Kansas City, KS, USAUniversity of Kansas School of Medicine, Kansas City, KS, USATexas Tech University, Lubbock, TX, USAUniversity of Kansas School of Medicine, Kansas City, KS, USAUniversity of Missouri Kansas City, Kansas City, MO, USAUniversity of Kansas School of Medicine, Kansas City, KS, USAUniversity of Kansas School of Medicine, Kansas City, KS, USAUniversity of Kansas School of Medicine, Kansas City, KS, USAClinical trials conducted with incarcerated populations are rare. We present a case example of one such jail-based cancer prevention clinical trial to demonstrate the importance of including a theory-driven approach to intervention framing, novel experimental designs to boost access to low-risk trials, and retention strategies for long-term follow-up of hard-to-reach populations. As such we offer a social determinant of health framework to ensure cancer prevention research is conducted through the lenses of health promotion and health equity. Deviations from the gold-standard randomized control design, transparent systematic allotment, and street-based outreach retention strategies contribute to the feasibility of conducting clinical trials in carceral settings and after people leave jail. Best practices presented can be used in design and conduct of future clinical trials with criminal legal system-involved populations.https://www.cambridge.org/core/product/identifier/S2059866123005617/type/journal_articleJailclinical trialsocial determinants of healthcancer prevention |
| spellingShingle | Pablo Kennedy Rubina Ratnaparkhi Jaehoon Lee Jason E. Glenn Patricia J. Kelly Kim S. Kimminau Stephanie Assimonye Megha Ramaswamy Case example of a jail-based cancer prevention clinical trial: Social determinants of health framework, novel experimental design, and retention strategies to facilitate long-term follow-up of clinical trial participants Journal of Clinical and Translational Science Jail clinical trial social determinants of health cancer prevention |
| title | Case example of a jail-based cancer prevention clinical trial: Social determinants of health framework, novel experimental design, and retention strategies to facilitate long-term follow-up of clinical trial participants |
| title_full | Case example of a jail-based cancer prevention clinical trial: Social determinants of health framework, novel experimental design, and retention strategies to facilitate long-term follow-up of clinical trial participants |
| title_fullStr | Case example of a jail-based cancer prevention clinical trial: Social determinants of health framework, novel experimental design, and retention strategies to facilitate long-term follow-up of clinical trial participants |
| title_full_unstemmed | Case example of a jail-based cancer prevention clinical trial: Social determinants of health framework, novel experimental design, and retention strategies to facilitate long-term follow-up of clinical trial participants |
| title_short | Case example of a jail-based cancer prevention clinical trial: Social determinants of health framework, novel experimental design, and retention strategies to facilitate long-term follow-up of clinical trial participants |
| title_sort | case example of a jail based cancer prevention clinical trial social determinants of health framework novel experimental design and retention strategies to facilitate long term follow up of clinical trial participants |
| topic | Jail clinical trial social determinants of health cancer prevention |
| url | https://www.cambridge.org/core/product/identifier/S2059866123005617/type/journal_article |
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