Concurrent Negative Impact of Undernutrition and Heart Failure on Functional and Cognitive Recovery in Hip Fracture Patients
Evidence on the effects of frailty, undernutrition, and heart failure (HF) on patients with hip fractures is scarce. This retrospective cohort study aimed to examine the effects of undernutrition and HF on outcomes in patients who underwent convalescent rehabilitation after hip fracture. Undernutrit...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-11-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/15/22/4800 |
| _version_ | 1797458206353522688 |
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| author | Shuichi Kamijikkoku Yoshihiro Yoshimura |
| author_facet | Shuichi Kamijikkoku Yoshihiro Yoshimura |
| author_sort | Shuichi Kamijikkoku |
| collection | DOAJ |
| description | Evidence on the effects of frailty, undernutrition, and heart failure (HF) on patients with hip fractures is scarce. This retrospective cohort study aimed to examine the effects of undernutrition and HF on outcomes in patients who underwent convalescent rehabilitation after hip fracture. Undernutrition was defined as body mass index (BMI) < 20.0 (Low BMI). Heart failure (HF) was defined as a B-type natriuretic peptide (BNP) > 100 (High BNP). The study outcomes included the Functional Independence Measure motor domain (FIM-motor) and cognitive domain (FIM-cognition) at discharge. To consider the effects of low BMI, high BNP, and the simultaneous presence of both (“low BMI and high BNP”), we used multivariate linear regression analyses to examine whether these were associated with the outcomes. A total of 110 (mean age 87.4 years, 24.8% male) were analyzed. As a result, low BMI (β = −0.088, <i>p</i> = 0.027) and high BNP (β = −0.053, <i>p</i> = 0.015), each alone, were significantly associated with the FIM motor at discharge, whereas the simultaneous presence of “low BMI and high BNP” was significantly associated with the FIM motor at discharge, while the strength of the association was greater than each association alone (β = −0.152, <i>p</i> = 0.010). Further, the simultaneous presence of “low BMI and high BNP” was significantly associated with FIM cognition at discharge (β = −0.109, <i>p</i> = 0.014). Comprehensive multidisciplinary management is needed, including preoperative or early postoperative nutritional support and rehabilitation, followed by rehabilitation nutrition care management, in patients with hip fracture. |
| first_indexed | 2024-03-09T16:33:46Z |
| format | Article |
| id | doaj.art-d5fef3c425b941f29e5a9dc1c8365f2a |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T16:33:46Z |
| publishDate | 2023-11-01 |
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| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-d5fef3c425b941f29e5a9dc1c8365f2a2023-11-24T14:59:22ZengMDPI AGNutrients2072-66432023-11-011522480010.3390/nu15224800Concurrent Negative Impact of Undernutrition and Heart Failure on Functional and Cognitive Recovery in Hip Fracture PatientsShuichi Kamijikkoku0Yoshihiro Yoshimura1Department of Cardiology Medicine, Kumamoto Rehabilitation Hospital, Kumamoto 869-1106, JapanCenter for Sarcopenia and Malnutrition Research, Kumamoto Rehabilitation Hospital, Kumamoto 869-1106, JapanEvidence on the effects of frailty, undernutrition, and heart failure (HF) on patients with hip fractures is scarce. This retrospective cohort study aimed to examine the effects of undernutrition and HF on outcomes in patients who underwent convalescent rehabilitation after hip fracture. Undernutrition was defined as body mass index (BMI) < 20.0 (Low BMI). Heart failure (HF) was defined as a B-type natriuretic peptide (BNP) > 100 (High BNP). The study outcomes included the Functional Independence Measure motor domain (FIM-motor) and cognitive domain (FIM-cognition) at discharge. To consider the effects of low BMI, high BNP, and the simultaneous presence of both (“low BMI and high BNP”), we used multivariate linear regression analyses to examine whether these were associated with the outcomes. A total of 110 (mean age 87.4 years, 24.8% male) were analyzed. As a result, low BMI (β = −0.088, <i>p</i> = 0.027) and high BNP (β = −0.053, <i>p</i> = 0.015), each alone, were significantly associated with the FIM motor at discharge, whereas the simultaneous presence of “low BMI and high BNP” was significantly associated with the FIM motor at discharge, while the strength of the association was greater than each association alone (β = −0.152, <i>p</i> = 0.010). Further, the simultaneous presence of “low BMI and high BNP” was significantly associated with FIM cognition at discharge (β = −0.109, <i>p</i> = 0.014). Comprehensive multidisciplinary management is needed, including preoperative or early postoperative nutritional support and rehabilitation, followed by rehabilitation nutrition care management, in patients with hip fracture.https://www.mdpi.com/2072-6643/15/22/4800frailtymalnutritionheart failurerehabilitation nutritionhip fracture |
| spellingShingle | Shuichi Kamijikkoku Yoshihiro Yoshimura Concurrent Negative Impact of Undernutrition and Heart Failure on Functional and Cognitive Recovery in Hip Fracture Patients Nutrients frailty malnutrition heart failure rehabilitation nutrition hip fracture |
| title | Concurrent Negative Impact of Undernutrition and Heart Failure on Functional and Cognitive Recovery in Hip Fracture Patients |
| title_full | Concurrent Negative Impact of Undernutrition and Heart Failure on Functional and Cognitive Recovery in Hip Fracture Patients |
| title_fullStr | Concurrent Negative Impact of Undernutrition and Heart Failure on Functional and Cognitive Recovery in Hip Fracture Patients |
| title_full_unstemmed | Concurrent Negative Impact of Undernutrition and Heart Failure on Functional and Cognitive Recovery in Hip Fracture Patients |
| title_short | Concurrent Negative Impact of Undernutrition and Heart Failure on Functional and Cognitive Recovery in Hip Fracture Patients |
| title_sort | concurrent negative impact of undernutrition and heart failure on functional and cognitive recovery in hip fracture patients |
| topic | frailty malnutrition heart failure rehabilitation nutrition hip fracture |
| url | https://www.mdpi.com/2072-6643/15/22/4800 |
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