DNA strand displacement based computational systems and their applications

DNA computing has become the focus of computing research due to its excellent parallel processing capability, data storage capacity, and low energy consumption characteristics. DNA computational units can be precisely programmed through the sequence specificity and base pair principle. Then, computa...

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Main Authors: Congzhou Chen, Jinda Wen, Zhibin Wen, Sijie Song, Xiaolong Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1120791/full
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author Congzhou Chen
Jinda Wen
Zhibin Wen
Sijie Song
Xiaolong Shi
author_facet Congzhou Chen
Jinda Wen
Zhibin Wen
Sijie Song
Xiaolong Shi
author_sort Congzhou Chen
collection DOAJ
description DNA computing has become the focus of computing research due to its excellent parallel processing capability, data storage capacity, and low energy consumption characteristics. DNA computational units can be precisely programmed through the sequence specificity and base pair principle. Then, computational units can be cascaded and integrated to form large DNA computing systems. Among them, DNA strand displacement (DSD) is the simplest but most efficient method for constructing DNA computing systems. The inputs and outputs of DSD are signal strands that can be transferred to the next unit. DSD has been used to construct logic gates, integrated circuits, artificial neural networks, etc. This review introduced the recent development of DSD-based computational systems and their applications. Some DSD-related tools and issues are also discussed.
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spelling doaj.art-d5ff03b776a746b8a2d0cf68c039c4282023-02-22T08:40:47ZengFrontiers Media S.A.Frontiers in Genetics1664-80212023-02-011410.3389/fgene.2023.11207911120791DNA strand displacement based computational systems and their applicationsCongzhou Chen0Jinda Wen1Zhibin Wen2Sijie Song3Xiaolong Shi4School of Computer Science, Beijing University of Technology, Beijing, ChinaInstitute of Computing Science and Technology, Guangzhou University, Guangzhou, ChinaInstitute of Computing Science and Technology, Guangzhou University, Guangzhou, ChinaInstitute of Computing Science and Technology, Guangzhou University, Guangzhou, ChinaInstitute of Computing Science and Technology, Guangzhou University, Guangzhou, ChinaDNA computing has become the focus of computing research due to its excellent parallel processing capability, data storage capacity, and low energy consumption characteristics. DNA computational units can be precisely programmed through the sequence specificity and base pair principle. Then, computational units can be cascaded and integrated to form large DNA computing systems. Among them, DNA strand displacement (DSD) is the simplest but most efficient method for constructing DNA computing systems. The inputs and outputs of DSD are signal strands that can be transferred to the next unit. DSD has been used to construct logic gates, integrated circuits, artificial neural networks, etc. This review introduced the recent development of DSD-based computational systems and their applications. Some DSD-related tools and issues are also discussed.https://www.frontiersin.org/articles/10.3389/fgene.2023.1120791/fullDNA strand displacementDNA computingintegrated circuitsartificial neural networkscancer detection
spellingShingle Congzhou Chen
Jinda Wen
Zhibin Wen
Sijie Song
Xiaolong Shi
DNA strand displacement based computational systems and their applications
Frontiers in Genetics
DNA strand displacement
DNA computing
integrated circuits
artificial neural networks
cancer detection
title DNA strand displacement based computational systems and their applications
title_full DNA strand displacement based computational systems and their applications
title_fullStr DNA strand displacement based computational systems and their applications
title_full_unstemmed DNA strand displacement based computational systems and their applications
title_short DNA strand displacement based computational systems and their applications
title_sort dna strand displacement based computational systems and their applications
topic DNA strand displacement
DNA computing
integrated circuits
artificial neural networks
cancer detection
url https://www.frontiersin.org/articles/10.3389/fgene.2023.1120791/full
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