A review on phytochemical, pharmacological attributes and therapeutic uses of Allium hookeri
Background: : Allium hookeri is a wild perennial herb within the genus Allium and having immense beneficial medicinal properties including anti-diabetic, anti-fungal, anti-ulcer, anti-obesity, hepatoprotective, neuroprotective, hypolipidemic, anti-inflammatory activity reported in various in vitro a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-05-01
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| Series: | Phytomedicine Plus |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667031322000483 |
| _version_ | 1811306768524902400 |
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| author | Barsha Deka Prasenjit Manna Jagat Chandra Borah Narayan Chandra Talukdar |
| author_facet | Barsha Deka Prasenjit Manna Jagat Chandra Borah Narayan Chandra Talukdar |
| author_sort | Barsha Deka |
| collection | DOAJ |
| description | Background: : Allium hookeri is a wild perennial herb within the genus Allium and having immense beneficial medicinal properties including anti-diabetic, anti-fungal, anti-ulcer, anti-obesity, hepatoprotective, neuroprotective, hypolipidemic, anti-inflammatory activity reported in various in vitro and in vivo experimental animals including clinical trial. It is also reported to induce reflux esophagitis and protection against Necrotic enteritis in broiler chicken, causing bodyweight increment when used as chicken feed. Because of the beneficial effects, it is consumed on a large scale by the people of Southeast Asian countries, including the people of Northeast Indian states of Manipur and Meghalaya, as a functional food. Method: : In preparation of this review article, an intense research was carried out for updated information on the scientific evaluation of the beneficial properties of Allium hookeri against various diseases and also the phytochemical constituents responsible for its beneficial effects till 2021. A literature review was performed on various platforms such as Google Scholar, Scifinder, PubMed and Science Direct. The data and interpretation of different publications were analyzed to achieve the objectives, organized with tables and pictorial illustrations and presented. Results: : Thirty references were found to list various traditional uses and results of investigations on scientific validation of the claim on the health benefits of A.hookeri from the literature review till 2021. Based on the phytochemical investigation, different authors identified 10 organosulphur volatile compounds, 11 organosulphur non-volatile compounds, and 42 other volatile compounds. 13 chemical constituents have been reported from the essential oil of A.hookeri. The other isolated compounds are linoleic acid, catechin, sinapic acid and ferulic acid. Along with the phytoconstituents, the diverse biological activities of different solvent extracts and fractions of this plant are also summarized in this review. Conclusions: : The different beneficial medicinal properties such as anti-fungal, anti-ulcer, anti-obesity, anti-diabetic, hepatoprotective, neuroprotective, hypolipidemic, anti-inflammatory, reflux esophagitis activity of A. hookeri are well documented through various scientific investigation. However, very few phytoconstituents have been isolated and purified from this plant to be tested for their role individually and in combination. Future research may be directed towards isolation, purification, characterization and identification of the chemical constituents responsible for the various beneficial effects of the plant. |
| first_indexed | 2024-04-13T08:51:29Z |
| format | Article |
| id | doaj.art-d6012251b8804ee0a217cbd090373f6c |
| institution | Directory Open Access Journal |
| issn | 2667-0313 |
| language | English |
| last_indexed | 2024-04-13T08:51:29Z |
| publishDate | 2022-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Phytomedicine Plus |
| spelling | doaj.art-d6012251b8804ee0a217cbd090373f6c2022-12-22T02:53:29ZengElsevierPhytomedicine Plus2667-03132022-05-0122100262A review on phytochemical, pharmacological attributes and therapeutic uses of Allium hookeriBarsha Deka0Prasenjit Manna1Jagat Chandra Borah2Narayan Chandra Talukdar3Chemical Biology Lab1, Institute of Advanced Study in Science and Technology (IASST) Paschim Boragaon, Guwahati-35, India; Department of Molecular Biology and Biotechnology, Cotton University, Panbazar, Guwahati-781001, Assam, IndiaChemical Biology Lab1, Institute of Advanced Study in Science and Technology (IASST) Paschim Boragaon, Guwahati-35, India; CSIR-North East Institute of Science and Technology, Biological Sciences and Technology Division, Jorhat, Assam, 785006, IndiaChemical Biology Lab1, Institute of Advanced Study in Science and Technology (IASST) Paschim Boragaon, Guwahati-35, India; Corresponding author at: Chemical Biology Laboratory1, Life science division, Institute of advanced study in science and technology, Paschim Boragaon, Assam, 781035Chemical Biology Lab1, Institute of Advanced Study in Science and Technology (IASST) Paschim Boragaon, Guwahati-35, India; Currently at Assam Down Town University, Panikhaiti, Assam, 781068, India; Corresponding author at: Assam Down Town University, Panikhaiti, Assam, 781068. Tel: 0361-227361; fax: 0361-2273062Background: : Allium hookeri is a wild perennial herb within the genus Allium and having immense beneficial medicinal properties including anti-diabetic, anti-fungal, anti-ulcer, anti-obesity, hepatoprotective, neuroprotective, hypolipidemic, anti-inflammatory activity reported in various in vitro and in vivo experimental animals including clinical trial. It is also reported to induce reflux esophagitis and protection against Necrotic enteritis in broiler chicken, causing bodyweight increment when used as chicken feed. Because of the beneficial effects, it is consumed on a large scale by the people of Southeast Asian countries, including the people of Northeast Indian states of Manipur and Meghalaya, as a functional food. Method: : In preparation of this review article, an intense research was carried out for updated information on the scientific evaluation of the beneficial properties of Allium hookeri against various diseases and also the phytochemical constituents responsible for its beneficial effects till 2021. A literature review was performed on various platforms such as Google Scholar, Scifinder, PubMed and Science Direct. The data and interpretation of different publications were analyzed to achieve the objectives, organized with tables and pictorial illustrations and presented. Results: : Thirty references were found to list various traditional uses and results of investigations on scientific validation of the claim on the health benefits of A.hookeri from the literature review till 2021. Based on the phytochemical investigation, different authors identified 10 organosulphur volatile compounds, 11 organosulphur non-volatile compounds, and 42 other volatile compounds. 13 chemical constituents have been reported from the essential oil of A.hookeri. The other isolated compounds are linoleic acid, catechin, sinapic acid and ferulic acid. Along with the phytoconstituents, the diverse biological activities of different solvent extracts and fractions of this plant are also summarized in this review. Conclusions: : The different beneficial medicinal properties such as anti-fungal, anti-ulcer, anti-obesity, anti-diabetic, hepatoprotective, neuroprotective, hypolipidemic, anti-inflammatory, reflux esophagitis activity of A. hookeri are well documented through various scientific investigation. However, very few phytoconstituents have been isolated and purified from this plant to be tested for their role individually and in combination. Future research may be directed towards isolation, purification, characterization and identification of the chemical constituents responsible for the various beneficial effects of the plant.http://www.sciencedirect.com/science/article/pii/S2667031322000483Allium hookeriPhytoconstituentsBiological activityOrganosulphur compounds |
| spellingShingle | Barsha Deka Prasenjit Manna Jagat Chandra Borah Narayan Chandra Talukdar A review on phytochemical, pharmacological attributes and therapeutic uses of Allium hookeri Phytomedicine Plus Allium hookeri Phytoconstituents Biological activity Organosulphur compounds |
| title | A review on phytochemical, pharmacological attributes and therapeutic uses of Allium hookeri |
| title_full | A review on phytochemical, pharmacological attributes and therapeutic uses of Allium hookeri |
| title_fullStr | A review on phytochemical, pharmacological attributes and therapeutic uses of Allium hookeri |
| title_full_unstemmed | A review on phytochemical, pharmacological attributes and therapeutic uses of Allium hookeri |
| title_short | A review on phytochemical, pharmacological attributes and therapeutic uses of Allium hookeri |
| title_sort | review on phytochemical pharmacological attributes and therapeutic uses of allium hookeri |
| topic | Allium hookeri Phytoconstituents Biological activity Organosulphur compounds |
| url | http://www.sciencedirect.com/science/article/pii/S2667031322000483 |
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