Development and Optimization of an Unbiased, Metagenomics-Based Pathogen Detection Workflow for Infectious Disease and Biosurveillance Applications

Development and Optimization of an Unbiased, Metagenomics-Based Pathogen Detection Workflow for Infectious Disease and Biosurveillance Applications

Rapid, specific, and sensitive identification of microbial pathogens is critical to infectious disease diagnosis and surveillance. Classical culture-based methods can be applied to a broad range of pathogens but have long turnaround times. Molecular methods, such as PCR, are time-effective but are n...

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Bibliographic Details
Main Authors: Kyle Parker, Hillary Wood, Joseph A. Russell, David Yarmosh, Alan Shteyman, John Bagnoli, Brittany Knight, Jacob R. Aspinwall, Jonathan Jacobs, Kristine Werking, Richard Winegar
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Tropical Medicine and Infectious Disease
Subjects:
biosurveillance
host depletion
infectious disease
next-generation sequencing
Online Access:https://www.mdpi.com/2414-6366/8/2/121

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