Tranexamic Acid versus Placebo to Prevent Blood Transfusion during Radical Cystectomy for Bladder Cancer (TACT): Study Protocol for a Randomized Controlled Trial

Tranexamic Acid versus Placebo to Prevent Blood Transfusion during Radical Cystectomy for Bladder Cancer (TACT): Study Protocol for a Randomized Controlled Trial

Abstract Background Radical cystectomy for bladder cancer is associated with a high risk of needing red blood cell transfusion. Tranexamic acid reduces blood loss during cardiac and orthopedic surgery, but no study has yet evaluated tranexamic acid use during cystectomy. Methods A randomized, double...

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Bibliographic Details
Main Authors: Rodney H. Breau, Luke T. Lavallée, Sonya Cnossen, Kelsey Witiuk, Ilias Cagiannos, Franco Momoli, Gregory Bryson, Salmaan Kanji, Christopher Morash, Alexis Turgeon, Ryan Zarychanski, Ranjeeta Mallick, Greg Knoll, Dean A. Fergusson
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Trials
Subjects:
Bladder cancer
Radical cystectomy
Tranexamic acid
Blood transfusion
Online Access:http://link.springer.com/article/10.1186/s13063-018-2626-3

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