Tumor antigens and immune subtypes guided mRNA vaccine development for kidney renal clear cell carcinoma

Tumor antigens and immune subtypes guided mRNA vaccine development for kidney renal clear cell carcinoma

Abstract Current treatment strategy for kidney renal clear cell carcinoma (KIRC) is limited. Tumor-associated antigens, especially neoantigen-based personalized mRNA vaccines represent new strategies and manifest clinical benefits in solid tumors, but only a small proportion of patients could benefi...

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Bibliographic Details
Main Authors: Hang Xu, Xiaonan Zheng, Shiyu Zhang, Xianyanling Yi, Tianyi Zhang, Qiang Wei, Hong Li, Jianzhong Ai
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Molecular Cancer
Subjects:
mRNA vaccine
Kidney renal clear cell carcinoma
Immunotherapy
Tumor antigens
Immune subtypes
Immune landscape
Online Access:https://doi.org/10.1186/s12943-021-01465-w

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