Corpora amylacea negatively correlate with hippocampal tau pathology in Alzheimer’s disease

Corpora amylacea negatively correlate with hippocampal tau pathology in Alzheimer’s disease

IntroductionSeverity and distribution of aggregated tau and neurofibrillary tangles (NFT) are strongly correlated with the clinical presentation of Alzheimer’s disease (AD). Clearance of aggregated tau could decrease the rate of NFT formation and delay AD onset. Recent studies implicate corpora amyl...

Full description

Bibliographic Details
Main Authors:	Julian D. Dallmeier, Ryan Gober, Regina T. Vontell, Ayled Barreda, Daniel A. Dorfsman, David A. Davis, Xiaoyan Sun, Daniel Brzostowicki, Illiana Bennett, Susanna P. Garamszegi, Connor M. Wander, Todd Cohen, William K. Scott
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-02-01
Series:	Frontiers in Neuroscience
Subjects:	corpora amylacea Alzheimer’s disease neuropathology neurofibrillary tangles APOE brain
Online Access:	https://www.frontiersin.org/articles/10.3389/fnins.2024.1286924/full

Similar Items

Parahippocampal corpora amylacea and neuronal lipofuscin in human aging
by: Bakić Mirjana, et al.
Published: (2013-12-01)

Corpora amylacea in temporal lobe epilepsy associated with hippocampal sclerosis
by: Ribeiro Marlise de Castro, et al.
Published: (2003-01-01)

Uncovering tau in wasteosomes (corpora amylacea) of Alzheimer’s disease patients
by: Marta Riba, et al.
Published: (2023-03-01)

The neuropathological diagnosis of Alzheimer’s disease
by: Michael A. DeTure, et al.
Published: (2019-08-01)

Wasteosomes (corpora amylacea) of human brain can be phagocytosed and digested by macrophages
by: Marta Riba, et al.
Published: (2022-10-01)

Corpora Amylacea in the Human Brain Exhibit Neoepitopes of a Carbohydrate Nature
by: Marta Riba, et al.
Published: (2021-06-01)

CORPORA AMYLACEA OF BRAIN TISSUE FROM NEURODEGENERATIVE DISEASES ARE STAINED WITH SPECIFIC ANTIFUNGAL ANTIBODIES
by: LUIS eCARRASCO, et al.
Published: (2016-03-01)

The hippocampal sparing subtype of Alzheimer’s disease assessed in neuropathology and in vivo tau positron emission tomography: a systematic review
by: Daniel Ferreira, et al.
Published: (2022-11-01)

Astrocytes are involved in the formation of corpora amylacea-like structures from neuronal debris in the CA1 region of the rat hippocampus after ischemia
by: Tae-Ryong Riew, et al.
Published: (2023-12-01)

Synthesis, Computational Pharmacokinetics Report, Conceptual DFT-Based Calculations and Anti-Acetylcholinesterase Activity of Hydroxyapatite Nanoparticles Derived From Acorus Calamus Plant Extract
by: Sushma Pradeep, et al.
Published: (2021-10-01)

Amyloid-Forming Corpora Amylacea and Spheroid-Type Amyloid Deposition: Comprehensive Analysis Using Immunohistochemistry, Proteomics, and a Literature Review
by: Shojiro Ichimata, et al.
Published: (2024-04-01)

Global neuropathologic severity of Alzheimer’s disease and locus coeruleus vulnerability influences plasma phosphorylated tau levels
by: Melissa E. Murray, et al.
Published: (2022-12-01)

Aducanumab: A new hope in Alzheimer's disease
by: Rouchan Ali, et al.
Published: (2022-09-01)

Toward a generalizable machine learning workflow for neurodegenerative disease staging with focus on neurofibrillary tangles
by: Juan C. Vizcarra, et al.
Published: (2023-12-01)

Distribution of corpora amylacea in the human midbrain: using synchrotron radiation phase-contrast microtomography, high-field magnetic resonance imaging, and histology
by: Ju Young Lee, et al.
Published: (2023-10-01)

The Role of Tau Pathology in Alzheimer’s Disease and Down Syndrome
by: Ann-Charlotte Granholm, et al.
Published: (2024-02-01)

Advances in Alzheimer’s disease therapeutics: biochemistry, exploring bioactive compounds and novel approaches
by: Ayomide Victor Atoki, et al.
Published: (2023-09-01)

Activation of Caspase-8 in the Alzheimer's Disease Brain
by: Troy T. Rohn, et al.
Published: (2001-12-01)

Okadaic acid induces damage of human neuroblastoma cell line SH-SY5Y
by: LU Ya-lan, ZHOU Li, HAN Yun-lin, WANG Ke-wei, QIN Chuan
Published: (2022-06-01)

Alzheimer’s disease: A Threat to mankind
by: Poorti Pandey, et al.
Published: (2011-12-01)

Corrigendum: Genetic Background Influences the Propagation of Tau Pathology in Transgenic Rodent Models of Tauopathy
by: Tomas Smolek, et al.
Published: (2020-02-01)

Pathology of different tau protein species in neurodegenerative diseases: Alzheimer’s disease, corticobasal degeneration, and progressive supranuclear palsy
by: Mohammad Majidi, et al.
Published: (2021-07-01)

Genetic Background Influences the Propagation of Tau Pathology in Transgenic Rodent Models of Tauopathy
by: Tomas Smolek, et al.
Published: (2019-12-01)

de novo MAPT mutation G335A causes severe brain atrophy, 3R and 4R PHF-tau pathology and early onset frontotemporal dementia
by: Kunie Ando, et al.
Published: (2020-06-01)

Caspase-9 Activation and Caspase Cleavage of tau in the Alzheimer's Disease Brain
by: Troy T. Rohn, et al.
Published: (2002-11-01)

Alzheimer’s Disease and Tau Self-Assembly: In the Search of the Missing Link
by: Andrea González, et al.
Published: (2022-04-01)

Body Fluid Biomarkers for Alzheimer’s Disease—An Up-To-Date Overview
by: Adrian Florian Bălașa, et al.
Published: (2020-10-01)

Transfusion with Blood Plasma from Young Mice Affects rTg4510 Transgenic Tau Mice Modeling of Alzheimer’s Disease
by: Carlos M. Hernandez, et al.
Published: (2023-05-01)

Exercise suppresses neuroinflammation for alleviating Alzheimer’s disease
by: Minghui Wang, et al.
Published: (2023-03-01)

Synaptic and metabolic gene expression alterations in neurons that are recipients of proteopathic tau seeds
by: Marta Perez-Rando, et al.
Published: (2020-10-01)

Fluctuations in neurofibrillary tangle density in Alzheimer’s disease revealed by Fourier (spectral) analysis
by: Richard Armstrong
Published: (2021-01-01)

Vitamin E therapy prevents the accumulation of congophilic amyloid plaques and neurofibrillary tangles in the hippocampus in a rat model of Alzheimer’s disease
by: Mehrdad Jahanshahi, et al.
Published: (2020-01-01)

Emerging Signal Regulating Potential of Genistein Against Alzheimer’s Disease: A Promising Molecule of Interest
by: Md. Sahab Uddin, et al.
Published: (2019-09-01)

Brain ethanolamine phospholipids, neuropathology and cognition: A comparative post-mortem analysis of structurally specific plasmalogen and phosphatidyl species
by: Dayan B. Goodenowe, et al.
Published: (2022-08-01)

Differentiating Alzheimer disease-associated aggregates with small molecules
by: Nicolette S. Honson, et al.
Published: (2007-12-01)

Development, initial validation, and application of a visual read method for [18F]MK‐6240 tau PET
by: Joanna L. Shuping, et al.
Published: (2023-01-01)

Association between APOE-ε4 allele and cognitive function is mediated by Alzheimer’s disease pathology: a population-based autopsy study in an admixed sample
by: Regina Silva Paradela, et al.
Published: (2023-12-01)

Subtypes of Alzheimer's Disease Display Distinct Network Abnormalities Extending Beyond Their Pattern of Brain Atrophy
by: Daniel Ferreira, et al.
Published: (2019-05-01)

Shaping the future of preclinical development of successful disease-modifying drugs against Alzheimer's disease: a systematic review of tau propagation models
by: Neha Basheer, et al.
Published: (2024-04-01)

A TOMM40/APOE allele encoding APOE‐E3 predicts high likelihood of late‐onset Alzheimer’s disease in autopsy cases
by: Selma M. Soyal, et al.
Published: (2020-08-01)