Asymmetric, amphiphilic RGD conjugated phthalocyanine for targeted photodynamic therapy of triple negative breast cancer

Asymmetric, amphiphilic RGD conjugated phthalocyanine for targeted photodynamic therapy of triple negative breast cancer

Abstract Targeted photodynamic therapy (TPDT) is considered superior to conventional photodynamic therapy due to the enhanced uptake of photosensitizers by tumor cells. In this paper, an amphiphilic and asymmetric cyclo-Arg-Gly-Asp-d-Tyr-Lys(cRGDyK)-conjugated silicon phthalocyanine (RSP) was synthe...

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Bibliographic Details
Main Authors: Rui Li, Yiming Zhou, Yijia Liu, Xingpeng Jiang, Wenlong Zeng, Zhuoran Gong, Gang Zheng, Desheng Sun, Zhifei Dai
Format: Article
Language:English
Published: Nature Publishing Group 2022-02-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-022-00906-2

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