RKC-B1 Blocks Activation of NF-κB and NLRP3 Signaling Pathways to Suppress Neuroinflammation in LPS-Stimulated Mice

RKC-B1 Blocks Activation of NF-κB and NLRP3 Signaling Pathways to Suppress Neuroinflammation in LPS-Stimulated Mice

RKC-B1 is a novel fermentation product obtained from the marine micromonospora FIM02-523A. Thus far, there have been few reports about the pharmacological activity of RKC-B1. In our present study, we investigated the anti-neuroinflammatory effects and the possible mechanism of RKC-B1 in LPS-stimulat...

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Bibliographic Details
Main Authors:	Man Liu, Ying-Lin Yang, Shan-Shan Zhang, Dong-Ni Liu, Lian-Hua Fang, Guan-Hua Du, Yue-Hua Wang
Format:	Article
Language:	English
Published:	MDPI AG 2021-07-01
Series:	Marine Drugs
Subjects:	RKC-B1 neuroinflammation lipopolysaccharide (LPS) NF-κB NLRP3
Online Access:	https://www.mdpi.com/1660-3397/19/8/429

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