Sildenafil in the treatment of pulmonary hypertension
The paper describes the clinical use of a phosphodiesterase 5 inhibitor (sildenafll) in a patient with primary pulmonary hypertension during a long-term controlled follow-up. The 6-year use of sildenafll as monotherapy for pulmonary hypertension had a significant positive effect as a decrease in the...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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Ltd. “The National Academy of Pediatric Science and Innovation”
2016-03-01
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| Series: | Rossijskij Vestnik Perinatologii i Pediatrii |
| Subjects: | |
| Online Access: | https://www.ped-perinatology.ru/jour/article/view/286 |
| _version_ | 1797875268710301696 |
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| author | O. S. Groznova I. V. Leontyeva O. V. Todorova |
| author_facet | O. S. Groznova I. V. Leontyeva O. V. Todorova |
| author_sort | O. S. Groznova |
| collection | DOAJ |
| description | The paper describes the clinical use of a phosphodiesterase 5 inhibitor (sildenafll) in a patient with primary pulmonary hypertension during a long-term controlled follow-up. The 6-year use of sildenafll as monotherapy for pulmonary hypertension had a significant positive effect as a decrease in the functional class of pulmonary hypertension from 3 to 1, an increase in exercise tolerance, improvements in echocardiographic parameters and biochemical markers (brain natriuretic peptide), and a rise in oxygen uptake during cardiorespiratory testing. |
| first_indexed | 2024-04-10T01:45:00Z |
| format | Article |
| id | doaj.art-d60d60c242d240c499dd0ffeb523afe8 |
| institution | Directory Open Access Journal |
| issn | 1027-4065 2500-2228 |
| language | Russian |
| last_indexed | 2024-04-10T01:45:00Z |
| publishDate | 2016-03-01 |
| publisher | Ltd. “The National Academy of Pediatric Science and Innovation” |
| record_format | Article |
| series | Rossijskij Vestnik Perinatologii i Pediatrii |
| spelling | doaj.art-d60d60c242d240c499dd0ffeb523afe82023-03-13T09:12:42ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282016-03-01596939710.21508/1027-4065-2014-59-6-103-110279Sildenafil in the treatment of pulmonary hypertensionO. S. Groznova0I. V. Leontyeva1O. V. Todorova2Научно-исследовательский клинический институт педиатрии, МоскваНаучно-исследовательский клинический институт педиатрии, МоскваНаучно-исследовательский клинический институт педиатрии, МоскваThe paper describes the clinical use of a phosphodiesterase 5 inhibitor (sildenafll) in a patient with primary pulmonary hypertension during a long-term controlled follow-up. The 6-year use of sildenafll as monotherapy for pulmonary hypertension had a significant positive effect as a decrease in the functional class of pulmonary hypertension from 3 to 1, an increase in exercise tolerance, improvements in echocardiographic parameters and biochemical markers (brain natriuretic peptide), and a rise in oxygen uptake during cardiorespiratory testing.https://www.ped-perinatology.ru/jour/article/view/286детилегочная артериальная гипертензияраспространенностьклассификацияклиническая картиналечениеингибитор фосфодиэстеразы-5силденафилкардиореспираторный тест. |
| spellingShingle | O. S. Groznova I. V. Leontyeva O. V. Todorova Sildenafil in the treatment of pulmonary hypertension Rossijskij Vestnik Perinatologii i Pediatrii дети легочная артериальная гипертензия распространенность классификация клиническая картина лечение ингибитор фосфодиэстеразы-5 силденафил кардиореспираторный тест. |
| title | Sildenafil in the treatment of pulmonary hypertension |
| title_full | Sildenafil in the treatment of pulmonary hypertension |
| title_fullStr | Sildenafil in the treatment of pulmonary hypertension |
| title_full_unstemmed | Sildenafil in the treatment of pulmonary hypertension |
| title_short | Sildenafil in the treatment of pulmonary hypertension |
| title_sort | sildenafil in the treatment of pulmonary hypertension |
| topic | дети легочная артериальная гипертензия распространенность классификация клиническая картина лечение ингибитор фосфодиэстеразы-5 силденафил кардиореспираторный тест. |
| url | https://www.ped-perinatology.ru/jour/article/view/286 |
| work_keys_str_mv | AT osgroznova sildenafilinthetreatmentofpulmonaryhypertension AT ivleontyeva sildenafilinthetreatmentofpulmonaryhypertension AT ovtodorova sildenafilinthetreatmentofpulmonaryhypertension |