TranSPHIRE: automated and feedback-optimized on-the-fly processing for cryo-EM

High-throughput single particle cryo-EM, for instance in drug research, requires the automation of the single particle analysis workflow. Here, the authors present TranSPHIRE, a software package that allows the fully-automated, feedback-driven processing of cryo-EM datasets during data acquisition.

Bibliographic Details
Main Authors: Markus Stabrin, Fabian Schoenfeld, Thorsten Wagner, Sabrina Pospich, Christos Gatsogiannis, Stefan Raunser
Format: Article
Language:English
Published: Nature Portfolio 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19513-2

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