TranSPHIRE: automated and feedback-optimized on-the-fly processing for cryo-EM
High-throughput single particle cryo-EM, for instance in drug research, requires the automation of the single particle analysis workflow. Here, the authors present TranSPHIRE, a software package that allows the fully-automated, feedback-driven processing of cryo-EM datasets during data acquisition.
Main Authors: | Markus Stabrin, Fabian Schoenfeld, Thorsten Wagner, Sabrina Pospich, Christos Gatsogiannis, Stefan Raunser |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-11-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-19513-2 |
Similar Items
-
Cryo-EM reveals the asymmetric assembly of squid hemocyanin
by: Yoshikazu Tanaka, et al.
Published: (2019-05-01) -
Accelerated 2D Classification With ISAC Using GPUs
by: Fabian Schöenfeld, et al.
Published: (2022-07-01) -
Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state.
by: Claudia Antoni, et al.
Published: (2020-08-01) -
Electron cryo-microscopy structure of the canonical TRPC4 ion channel
by: Deivanayagabarathy Vinayagam, et al.
Published: (2018-05-01) -
High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism
by: Sabrina Pospich, et al.
Published: (2021-11-01)