Comparison of Short-Term Clinical Outcome of Non-ST Elevation versus ST Elevation Myocardial Infarction

Background: Studies on the prognosis of ST elevation myocardial infarction (STEMI) versus non-ST elevation myocardial infarction (non-STEMI) have shown different results. The present study was designed to compare the early outcome and left ventricular systolic function of patients with ST and non-ST...

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Main Authors: Hakimeh Sadeghian, Mehrdad Sheikhvatan, Mehran Mahmoodian, Mahmood Sheikhfathollahi, Elham Hakki, Afsaneh Sadeghian, Behnaz Behnam, Ali Mohammad Haji Zeinali, Vahid Semnani
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2009-04-01
Series:Journal of Tehran University Heart Center
Subjects:
Online Access:https://jthc.tums.ac.ir/index.php/jthc/article/view/126
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author Hakimeh Sadeghian
Mehrdad Sheikhvatan
Mehran Mahmoodian
Mahmood Sheikhfathollahi
Elham Hakki
Afsaneh Sadeghian
Behnaz Behnam
Ali Mohammad Haji Zeinali
Vahid Semnani
author_facet Hakimeh Sadeghian
Mehrdad Sheikhvatan
Mehran Mahmoodian
Mahmood Sheikhfathollahi
Elham Hakki
Afsaneh Sadeghian
Behnaz Behnam
Ali Mohammad Haji Zeinali
Vahid Semnani
author_sort Hakimeh Sadeghian
collection DOAJ
description Background: Studies on the prognosis of ST elevation myocardial infarction (STEMI) versus non-ST elevation myocardial infarction (non-STEMI) have shown different results. The present study was designed to compare the early outcome and left ventricular systolic function of patients with ST and non-ST elevation myocardial infarction. Methods: The patients' information was derived from 10,065 consecutive patients hospitalized in Tehran Heart Center with acute MI (2007 patients with STEMI and 8058 with non-STEMI). The baseline clinical characteristics, post-MI complications, left ventricular systolic functions, and 30-day mortality rates were compared. Results: A history of current cigarette smoking, opium addiction, and brain stroke was more frequent in the STEMI patients, whereas hyperlipidemia, hypertension, and obesity were found more in the non-STEMI group. Ejection fraction was higher in the non-STEMI patients than that in the STEMI group, and anterior wall infarction was detected more frequently in the STEMI cases. A history of coronary artery bypass grafting and also percutaneous coronary intervention was observed more in the non-STEMI group. Amongst the in-hospital complications, ventricular arrhythmias (1.4 vs. 0.5, P<0.001) and pulmonary edema (0.4 vs. 0.1, P=0.002) were more prevalent in the STEMI cases. The 30-day mortality rate in the STEMI group was higher than that in the non-STEMI group (5.5 vs. 2.4, P<0.001). Early mortality in both groups was dependant on advanced age, diabetes mellitus, post-MI bradycardia, and atrioventricular block. Also, female gender and pulmonary edema in the STEMI group and family history of MI in the non-STEMI patients could predict 30-day mortality.   Conclusion: There were several differences in the baseline characteristics and early outcome between the two types of STEMI and non-STEMI. The 30-day mortality rate was higher in the STEMI group than that in the non-STEMI group.
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spelling doaj.art-d611e1fbe78d4377bac6e9d7ae37a9672022-12-22T02:50:01ZengTehran University of Medical SciencesJournal of Tehran University Heart Center1735-86202008-23712009-04-0142124Comparison of Short-Term Clinical Outcome of Non-ST Elevation versus ST Elevation Myocardial InfarctionHakimeh Sadeghian0Mehrdad Sheikhvatan1Mehran Mahmoodian2Mahmood Sheikhfathollahi3Elham Hakki4Afsaneh Sadeghian5Behnaz Behnam6Ali Mohammad Haji Zeinali7Vahid Semnani8Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.Shahrood University of Medical Sciences, Shahrood, Iran.Fatemieh Hospital, Semnan University of Medical Sciences, Semnan, Iran.Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.Fatemieh Hospital, Semnan University of Medical Sciences, Semnan, Iran.Background: Studies on the prognosis of ST elevation myocardial infarction (STEMI) versus non-ST elevation myocardial infarction (non-STEMI) have shown different results. The present study was designed to compare the early outcome and left ventricular systolic function of patients with ST and non-ST elevation myocardial infarction. Methods: The patients' information was derived from 10,065 consecutive patients hospitalized in Tehran Heart Center with acute MI (2007 patients with STEMI and 8058 with non-STEMI). The baseline clinical characteristics, post-MI complications, left ventricular systolic functions, and 30-day mortality rates were compared. Results: A history of current cigarette smoking, opium addiction, and brain stroke was more frequent in the STEMI patients, whereas hyperlipidemia, hypertension, and obesity were found more in the non-STEMI group. Ejection fraction was higher in the non-STEMI patients than that in the STEMI group, and anterior wall infarction was detected more frequently in the STEMI cases. A history of coronary artery bypass grafting and also percutaneous coronary intervention was observed more in the non-STEMI group. Amongst the in-hospital complications, ventricular arrhythmias (1.4 vs. 0.5, P<0.001) and pulmonary edema (0.4 vs. 0.1, P=0.002) were more prevalent in the STEMI cases. The 30-day mortality rate in the STEMI group was higher than that in the non-STEMI group (5.5 vs. 2.4, P<0.001). Early mortality in both groups was dependant on advanced age, diabetes mellitus, post-MI bradycardia, and atrioventricular block. Also, female gender and pulmonary edema in the STEMI group and family history of MI in the non-STEMI patients could predict 30-day mortality.   Conclusion: There were several differences in the baseline characteristics and early outcome between the two types of STEMI and non-STEMI. The 30-day mortality rate was higher in the STEMI group than that in the non-STEMI group.https://jthc.tums.ac.ir/index.php/jthc/article/view/126Myocardial infarctionOutcome assessmentMortality
spellingShingle Hakimeh Sadeghian
Mehrdad Sheikhvatan
Mehran Mahmoodian
Mahmood Sheikhfathollahi
Elham Hakki
Afsaneh Sadeghian
Behnaz Behnam
Ali Mohammad Haji Zeinali
Vahid Semnani
Comparison of Short-Term Clinical Outcome of Non-ST Elevation versus ST Elevation Myocardial Infarction
Journal of Tehran University Heart Center
Myocardial infarction
Outcome assessment
Mortality
title Comparison of Short-Term Clinical Outcome of Non-ST Elevation versus ST Elevation Myocardial Infarction
title_full Comparison of Short-Term Clinical Outcome of Non-ST Elevation versus ST Elevation Myocardial Infarction
title_fullStr Comparison of Short-Term Clinical Outcome of Non-ST Elevation versus ST Elevation Myocardial Infarction
title_full_unstemmed Comparison of Short-Term Clinical Outcome of Non-ST Elevation versus ST Elevation Myocardial Infarction
title_short Comparison of Short-Term Clinical Outcome of Non-ST Elevation versus ST Elevation Myocardial Infarction
title_sort comparison of short term clinical outcome of non st elevation versus st elevation myocardial infarction
topic Myocardial infarction
Outcome assessment
Mortality
url https://jthc.tums.ac.ir/index.php/jthc/article/view/126
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