Hybrid Neuromuscular Training Improves Cardiometabolic Health and Alters Redox Status in Inactive Overweight and Obese Women: A Randomized Controlled Trial
This randomized controlled trial investigated the effects of a 5-month high-intensity hybrid-type neuromuscular training program with nontraditional implements on cardiometabolic health, redox status, and cardiovascular disease (CVD) risk in inactive overweight and obese women. Forty-nine inactive f...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-10-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/10/10/1601 |
| _version_ | 1827680293486592000 |
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| author | Alexios Batrakoulis Athanasios Z. Jamurtas Dimitrios Draganidis Kalliopi Georgakouli Panagiotis Tsimeas Athanasios Poulios Niki Syrou Chariklia K. Deli Konstantinos Papanikolaou Symeon Tournis Ioannis G. Fatouros |
| author_facet | Alexios Batrakoulis Athanasios Z. Jamurtas Dimitrios Draganidis Kalliopi Georgakouli Panagiotis Tsimeas Athanasios Poulios Niki Syrou Chariklia K. Deli Konstantinos Papanikolaou Symeon Tournis Ioannis G. Fatouros |
| author_sort | Alexios Batrakoulis |
| collection | DOAJ |
| description | This randomized controlled trial investigated the effects of a 5-month high-intensity hybrid-type neuromuscular training program with nontraditional implements on cardiometabolic health, redox status, and cardiovascular disease (CVD) risk in inactive overweight and obese women. Forty-nine inactive female participants with overweight and obesity (age: 36.4 ± 4.4 years; BMI: 29.1 ± 2.9 kg/m<sup>2</sup>) were randomly assigned to either a control (C, <i>n</i> = 21) or a training group (TR, <i>n</i> = 28). TR followed a 20-week supervised, progressive, time-efficient (3 days/week; 6–15 min net exercise time) program implementing loaded fundamental movement patterns with prescribed work-to-rest time intervals (20–40 s, 1:2, 1:1, 2:1) in a circuit fashion (2–3 rounds). Cardiometabolic risk factors were measured at baseline and post-training as secondary outcomes of a larger randomized controlled trial. At post-intervention, TR demonstrated favorable changes in resting heart rate (−7%, <i>p</i> = 0.043), high-density lipoprotein (+18.1%, <i>p</i> = 0.029), atherogenic index (−17%, <i>p</i> = 0.045), mean arterial pressure (−4.5%, <i>p</i> = 0.03), waist circumference (−6.2%, <i>p</i> = 0.005), waist-to-hip ratio (−4.6%; <i>p</i> = 0.015), metabolic syndrome severity score (−222%, <i>p</i> = 0.024), full 30-year CVD risk (−15.8%, <i>p</i> = 0.002) and hard 30-year CVD risk (−17.6%, <i>p</i> = 0.01), vascular age (−7.8%, <i>p</i> = 0.002), protein carbonyls (−45.7%, <i>p</i> = 0.001), catalase activity (+15.2%, <i>p</i> = 0.023), and total antioxidant capacity (+11.4%, <i>p</i> = 0.002) relative to C. Additionally, TR induced beneficial changes in fasting glucose (−3.4%, <i>p</i> = 0.002), homeostatic model assessment for insulin resistance (−15.7%, <i>p</i> < 0.001), diastolic blood pressure (−5.6%, <i>p</i> < 0.001), reduced glutathione (+39.8%, <i>p</i> < 0.001), 10-year CVD risk (−17.4%, <i>p</i> = 0.011), and total bilirubin (−21.7%, <i>p</i> < 0.001) compared to baseline. These results suggest that hybrid-type neuromuscular training may improve aspects of cardiometabolic health and antioxidant status in inactive overweight and obese women providing a time-efficient (~100 min/week) exercise approach in a real-world gym setting. |
| first_indexed | 2024-03-10T06:45:44Z |
| format | Article |
| id | doaj.art-d6130bbc777345d5bf7aa922926a2526 |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-10T06:45:44Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-d6130bbc777345d5bf7aa922926a25262023-11-22T17:16:35ZengMDPI AGAntioxidants2076-39212021-10-011010160110.3390/antiox10101601Hybrid Neuromuscular Training Improves Cardiometabolic Health and Alters Redox Status in Inactive Overweight and Obese Women: A Randomized Controlled TrialAlexios Batrakoulis0Athanasios Z. Jamurtas1Dimitrios Draganidis2Kalliopi Georgakouli3Panagiotis Tsimeas4Athanasios Poulios5Niki Syrou6Chariklia K. Deli7Konstantinos Papanikolaou8Symeon Tournis9Ioannis G. Fatouros10Department of Physical Education and Sport Sciences, University of Thessaly, 42100 Trikala, GreeceDepartment of Physical Education and Sport Sciences, University of Thessaly, 42100 Trikala, GreeceDepartment of Physical Education and Sport Sciences, University of Thessaly, 42100 Trikala, GreeceDepartment of Nutrition and Dietetics, University of Thessaly, 42100 Trikala, GreeceDepartment of Physical Education and Sport Sciences, University of Thessaly, 42100 Trikala, GreeceDepartment of Physical Education and Sport Sciences, University of Thessaly, 42100 Trikala, GreeceDepartment of Physical Education and Sport Sciences, University of Thessaly, 42100 Trikala, GreeceDepartment of Physical Education and Sport Sciences, University of Thessaly, 42100 Trikala, GreeceDepartment of Physical Education and Sport Sciences, University of Thessaly, 42100 Trikala, GreeceLaboratory for Research of the Musculoskeletal System “Th. Garofalidis”, National and Kapodistrian University of Athens, 14561 Athens, GreeceDepartment of Physical Education and Sport Sciences, University of Thessaly, 42100 Trikala, GreeceThis randomized controlled trial investigated the effects of a 5-month high-intensity hybrid-type neuromuscular training program with nontraditional implements on cardiometabolic health, redox status, and cardiovascular disease (CVD) risk in inactive overweight and obese women. Forty-nine inactive female participants with overweight and obesity (age: 36.4 ± 4.4 years; BMI: 29.1 ± 2.9 kg/m<sup>2</sup>) were randomly assigned to either a control (C, <i>n</i> = 21) or a training group (TR, <i>n</i> = 28). TR followed a 20-week supervised, progressive, time-efficient (3 days/week; 6–15 min net exercise time) program implementing loaded fundamental movement patterns with prescribed work-to-rest time intervals (20–40 s, 1:2, 1:1, 2:1) in a circuit fashion (2–3 rounds). Cardiometabolic risk factors were measured at baseline and post-training as secondary outcomes of a larger randomized controlled trial. At post-intervention, TR demonstrated favorable changes in resting heart rate (−7%, <i>p</i> = 0.043), high-density lipoprotein (+18.1%, <i>p</i> = 0.029), atherogenic index (−17%, <i>p</i> = 0.045), mean arterial pressure (−4.5%, <i>p</i> = 0.03), waist circumference (−6.2%, <i>p</i> = 0.005), waist-to-hip ratio (−4.6%; <i>p</i> = 0.015), metabolic syndrome severity score (−222%, <i>p</i> = 0.024), full 30-year CVD risk (−15.8%, <i>p</i> = 0.002) and hard 30-year CVD risk (−17.6%, <i>p</i> = 0.01), vascular age (−7.8%, <i>p</i> = 0.002), protein carbonyls (−45.7%, <i>p</i> = 0.001), catalase activity (+15.2%, <i>p</i> = 0.023), and total antioxidant capacity (+11.4%, <i>p</i> = 0.002) relative to C. Additionally, TR induced beneficial changes in fasting glucose (−3.4%, <i>p</i> = 0.002), homeostatic model assessment for insulin resistance (−15.7%, <i>p</i> < 0.001), diastolic blood pressure (−5.6%, <i>p</i> < 0.001), reduced glutathione (+39.8%, <i>p</i> < 0.001), 10-year CVD risk (−17.4%, <i>p</i> = 0.011), and total bilirubin (−21.7%, <i>p</i> < 0.001) compared to baseline. These results suggest that hybrid-type neuromuscular training may improve aspects of cardiometabolic health and antioxidant status in inactive overweight and obese women providing a time-efficient (~100 min/week) exercise approach in a real-world gym setting.https://www.mdpi.com/2076-3921/10/10/1601antioxidant capacityblood lipidsglycemic controlinterval exercise trainingmetabolic syndrome severity |
| spellingShingle | Alexios Batrakoulis Athanasios Z. Jamurtas Dimitrios Draganidis Kalliopi Georgakouli Panagiotis Tsimeas Athanasios Poulios Niki Syrou Chariklia K. Deli Konstantinos Papanikolaou Symeon Tournis Ioannis G. Fatouros Hybrid Neuromuscular Training Improves Cardiometabolic Health and Alters Redox Status in Inactive Overweight and Obese Women: A Randomized Controlled Trial Antioxidants antioxidant capacity blood lipids glycemic control interval exercise training metabolic syndrome severity |
| title | Hybrid Neuromuscular Training Improves Cardiometabolic Health and Alters Redox Status in Inactive Overweight and Obese Women: A Randomized Controlled Trial |
| title_full | Hybrid Neuromuscular Training Improves Cardiometabolic Health and Alters Redox Status in Inactive Overweight and Obese Women: A Randomized Controlled Trial |
| title_fullStr | Hybrid Neuromuscular Training Improves Cardiometabolic Health and Alters Redox Status in Inactive Overweight and Obese Women: A Randomized Controlled Trial |
| title_full_unstemmed | Hybrid Neuromuscular Training Improves Cardiometabolic Health and Alters Redox Status in Inactive Overweight and Obese Women: A Randomized Controlled Trial |
| title_short | Hybrid Neuromuscular Training Improves Cardiometabolic Health and Alters Redox Status in Inactive Overweight and Obese Women: A Randomized Controlled Trial |
| title_sort | hybrid neuromuscular training improves cardiometabolic health and alters redox status in inactive overweight and obese women a randomized controlled trial |
| topic | antioxidant capacity blood lipids glycemic control interval exercise training metabolic syndrome severity |
| url | https://www.mdpi.com/2076-3921/10/10/1601 |
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