Quantification of Venetoclax for Therapeutic Drug Monitoring in Chinese Acute Myeloid Leukemia Patients by a Validated UPLC-MS/MS Method

Quantification of Venetoclax for Therapeutic Drug Monitoring in Chinese Acute Myeloid Leukemia Patients by a Validated UPLC-MS/MS Method

Venetoclax has emerged as a breakthrough for treatment of leukemia with a wide interindividual variability in pharmacokinetics. Herein, a rapid, sensitive, and reliable UPLC-MS/MS method for quantification of venetoclax in plasma was developed and validated. The method was operated in the multiple-r...

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Bibliographic Details
Main Authors: Xi Yang, Chen Mei, Xiaoying He, Lingjuan He, Xiaoyang Lu, Hongyan Tong, Yan Lou
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Molecules
Subjects:
venetoclax
UPLC-MS/MS
therapeutic drug monitoring
Online Access:https://www.mdpi.com/1420-3049/27/5/1607

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