Lactobacillus spp. act in synergy to attenuate splenomegaly and lymphadenopathy in lupus-prone MRL/lpr mice

Lactobacillus spp. act in synergy to attenuate splenomegaly and lymphadenopathy in lupus-prone MRL/lpr mice

Commensal bacteria and the immune system have a close and strong relationship that maintains a balance to control inflammation. Alterations of the microbiota, known as dysbiosis, can direct reactivity to self-antigens not only in the intestinal mucosa but also at the systemic level. Our laboratory p...

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Bibliographic Details
Main Authors:	Xavier Cabana-Puig, Qinghui Mu, Ran Lu, Brianna Swartwout, Leila Abdelhamid, Jing Zhu, Meeta Prakash, Thomas E. Cecere, Zhuang Wang, Sabrina Callaway, Sha Sun, Christopher M. Reilly, S. Ansar Ahmed, Xin M. Luo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-07-01
Series:	Frontiers in Immunology
Subjects:	lupus gut microbiota Lactobacillus type 1 regulatory T cells memory T cells double-negative T cells
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.923754/full

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