A cross-sectional study evaluating tick-borne encephalitis vaccine uptake and timeliness among adults in Switzerland.
The goal of this study was to evaluate timeliness of Tick-borne Encephalitis vaccination uptake among adults in Switzerland. In this cross-sectional survey, we collected vaccination records from randomly selected adults 18-79 throughout Switzerland. Of 4,626 participants, data from individuals recei...
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| Language: | English |
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Public Library of Science (PLoS)
2021-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0247216&type=printable |
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| author | Kyra D Zens Vasiliki Baroutsou Philipp Sinniger Phung Lang |
| author_facet | Kyra D Zens Vasiliki Baroutsou Philipp Sinniger Phung Lang |
| author_sort | Kyra D Zens |
| collection | DOAJ |
| description | The goal of this study was to evaluate timeliness of Tick-borne Encephalitis vaccination uptake among adults in Switzerland. In this cross-sectional survey, we collected vaccination records from randomly selected adults 18-79 throughout Switzerland. Of 4,626 participants, data from individuals receiving at least 1 TBE vaccination (n = 1875) were evaluated. We determined year and age of first vaccination and vaccine compliance, evaluating dose timeliness. Participants were considered "on time" if they received doses according to the recommended schedule ± a 15% tolerance period. 45% of participants received their first TBE vaccination between 2006 and 2009, which corresponds to a 2006 change in the official recommendation for TBE vaccination in Switzerland. 25% were first vaccinated aged 50+ (mean age 37). More than 95% of individuals receiving the first dose also received the second; ~85% of those receiving the second dose received the third. For individuals completing the primary series, 30% received 3 doses of Encepur, 58% received 3 doses of FSME-Immun, and 12% received a combination. According to "conventional" schedules, 88% and 79% of individuals received their second and third doses "on time", respectively. 20% of individuals receiving Encepur received their third dose "too early". Of individuals completing primary vaccination, 19% were overdue for a booster. Among the 31% of subjects receiving a booster, mean time to first booster was 7.1 years. We estimate that a quarter of adults in Switzerland were first vaccinated for TBE aged 50+. Approximately 80% of participants receiving at least one vaccine dose completed the primary series. We further estimate that 66% of individuals completing the TBE vaccination primary series did so with a single vaccine type and adhered to the recommended schedule. |
| first_indexed | 2024-04-11T20:44:45Z |
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| id | doaj.art-d618eefd01e54e7e8fcc2a55ff46883d |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2025-03-14T07:10:05Z |
| publishDate | 2021-01-01 |
| publisher | Public Library of Science (PLoS) |
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| series | PLoS ONE |
| spelling | doaj.art-d618eefd01e54e7e8fcc2a55ff46883d2025-03-04T05:32:23ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-011612e024721610.1371/journal.pone.0247216A cross-sectional study evaluating tick-borne encephalitis vaccine uptake and timeliness among adults in Switzerland.Kyra D ZensVasiliki BaroutsouPhilipp SinnigerPhung LangThe goal of this study was to evaluate timeliness of Tick-borne Encephalitis vaccination uptake among adults in Switzerland. In this cross-sectional survey, we collected vaccination records from randomly selected adults 18-79 throughout Switzerland. Of 4,626 participants, data from individuals receiving at least 1 TBE vaccination (n = 1875) were evaluated. We determined year and age of first vaccination and vaccine compliance, evaluating dose timeliness. Participants were considered "on time" if they received doses according to the recommended schedule ± a 15% tolerance period. 45% of participants received their first TBE vaccination between 2006 and 2009, which corresponds to a 2006 change in the official recommendation for TBE vaccination in Switzerland. 25% were first vaccinated aged 50+ (mean age 37). More than 95% of individuals receiving the first dose also received the second; ~85% of those receiving the second dose received the third. For individuals completing the primary series, 30% received 3 doses of Encepur, 58% received 3 doses of FSME-Immun, and 12% received a combination. According to "conventional" schedules, 88% and 79% of individuals received their second and third doses "on time", respectively. 20% of individuals receiving Encepur received their third dose "too early". Of individuals completing primary vaccination, 19% were overdue for a booster. Among the 31% of subjects receiving a booster, mean time to first booster was 7.1 years. We estimate that a quarter of adults in Switzerland were first vaccinated for TBE aged 50+. Approximately 80% of participants receiving at least one vaccine dose completed the primary series. We further estimate that 66% of individuals completing the TBE vaccination primary series did so with a single vaccine type and adhered to the recommended schedule.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0247216&type=printable |
| spellingShingle | Kyra D Zens Vasiliki Baroutsou Philipp Sinniger Phung Lang A cross-sectional study evaluating tick-borne encephalitis vaccine uptake and timeliness among adults in Switzerland. PLoS ONE |
| title | A cross-sectional study evaluating tick-borne encephalitis vaccine uptake and timeliness among adults in Switzerland. |
| title_full | A cross-sectional study evaluating tick-borne encephalitis vaccine uptake and timeliness among adults in Switzerland. |
| title_fullStr | A cross-sectional study evaluating tick-borne encephalitis vaccine uptake and timeliness among adults in Switzerland. |
| title_full_unstemmed | A cross-sectional study evaluating tick-borne encephalitis vaccine uptake and timeliness among adults in Switzerland. |
| title_short | A cross-sectional study evaluating tick-borne encephalitis vaccine uptake and timeliness among adults in Switzerland. |
| title_sort | cross sectional study evaluating tick borne encephalitis vaccine uptake and timeliness among adults in switzerland |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0247216&type=printable |
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