A novel ATG5 interaction with Ku70 potentiates DNA repair upon genotoxic stress
Abstract The maintenance of cellular homeostasis in living organisms requires a balance between anabolic and catabolic reactions. Macroautophagy (autophagy herein) is determined as one of the major catabolic reactions. Autophagy is an evolutionarily conserved stress response pathway that is activate...
Main Authors: | Sinem Demirbag-Sarikaya, Yunus Akkoc, Sıla Turgut, Secil Erbil-Bilir, Nur Mehpare Kocaturk, Joern Dengjel, Devrim Gozuacik |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-05-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-11704-9 |
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