Betulinic acid and glycyrrhetinic acid derived piperazinyl spacered rhodamine B conjugates are highly cytotoxic and necrotic

Betulinic acid and glycyrrhetinic acid derived piperazinyl spacered rhodamine B conjugates are highly cytotoxic and necrotic

Pentacyclic triterpene-piperazine-rhodamine B conjugates with ursane or oleanane backbones have been shown in the past to be highly cytotoxic thereby acting as mitocans. Starting from betulinic acid or glycyrrhetinic acid, new analogues were now made available, and their cytotoxic activity was inves...

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Bibliographic Details
Main Authors:	Marie Kozubek, Sophie Hoenke, Hans-Peter Deigner, René Csuk
Format:	Article
Language:	English
Published:	Elsevier 2022-01-01
Series:	Results in Chemistry
Subjects:	Betulin Betulinic acid Glycyrrhetinic acid Cytotoxicity Rhodamine B conjugates
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211715622001485

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