Glycyrrhizic Acid-Induced Differentiation Repressed Stemness in Hepatocellular Carcinoma by Targeting c-Jun N-Terminal Kinase 1

Glycyrrhizic Acid-Induced Differentiation Repressed Stemness in Hepatocellular Carcinoma by Targeting c-Jun N-Terminal Kinase 1

Hepatocellular carcinoma (HCC) is one of the most common malignant cancers with poor prognosis and high incidence. Cancer stem cells play a vital role in tumor initiation and malignancy. The degree of differentiation of HCC is closely related to its stemness. Glycyrrhizic acid (GA) plays a critical...

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Bibliographic Details
Main Authors: Shijiao Cai, Zhun Bi, Yunpeng Bai, Heng Zhang, Denghui Zhai, Cui Xiao, Yuanhao Tang, Lan Yang, Xiaoyun Zhang, Kun Li, Ru Yang, Yanrong Liu, Shuang Chen, Tao Sun, Huijuan Liu, Cheng Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Oncology
Subjects:
glycyrrhizic acid
stemness
differentiation
JNK1
sorafenib
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01431/full

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