Robust species taxonomy assignment algorithm for 16S rRNA NGS reads: application to oral carcinoma samples

Robust species taxonomy assignment algorithm for 16S rRNA NGS reads: application to oral carcinoma samples

Background: Usefulness of next-generation sequencing (NGS) in assessing bacteria associated with oral squamous cell carcinoma (OSCC) has been undermined by inability to classify reads to the species level. Objective: The purpose of this study was to develop a robust algorithm for species-level class...

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Bibliographic Details
Main Authors: Nezar Noor Al-Hebshi, Akram Thabet Nasher, Ali Mohamed Idris, Tsute Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2015-09-01
Series:Journal of Oral Microbiology
Subjects:
bacteria
cancer
next-generation sequencing
OSCC
pyrosequencing
taxonomy
Online Access:http://www.journaloforalmicrobiology.net/index.php/jom/article/view/28934/42434

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