A retrospective observational study to analyze recruitment paradigms in the treatment of hypoxemic COVID-19 patients admitted in the intensive care unit of a tertiary care institute in India
Introduction: This retrospective study attempted to assess the recruitability of the lungs that were affected by acute respiratory distress syndrome (ARDS) due to COVID-19. This was done with the combined use of transpulmonary pressure monitoring (to limit the stress), measurement of end-expiratory...
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| Format: | Article |
| Language: | English |
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Jaypee Brothers Medical Publisher
2022-01-01
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| Series: | Indian Journal of Respiratory Care |
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| Online Access: | http://www.ijrc.in/article.asp?issn=2277-9019;year=2022;volume=11;issue=3;spage=246;epage=252;aulast=Saseedharan |
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| author | Sanjith Saseedharan Vaijaynti Kadam Shalaka Patil Aakash Soni Ashish Yadav Rujuta Bagade Ipshita Panigrahi Namya Miglani |
| author_facet | Sanjith Saseedharan Vaijaynti Kadam Shalaka Patil Aakash Soni Ashish Yadav Rujuta Bagade Ipshita Panigrahi Namya Miglani |
| author_sort | Sanjith Saseedharan |
| collection | DOAJ |
| description | Introduction: This retrospective study attempted to assess the recruitability of the lungs that were affected by acute respiratory distress syndrome (ARDS) due to COVID-19. This was done with the combined use of transpulmonary pressure monitoring (to limit the stress), measurement of end-expiratory lung volume (EELV) (to measure the actual volume gain and be within limits of strain), electrical impedance tomography (EIT), and compliance (to diagnose overdistension). Recruitment was judged clinically by an increase in the SpO2 values. Methods: Retrospective data from the charts and progress sheets were collected from 27 patients admitted to the intensive care unit (between February 2021 and June 2021) with a ratio of arterial Partial pressure of oxygen (PaO2 in mmHg) to fractional inspired oxygen (FiO2) <150 (i.e., PaO2/FiO2 <150) with a diagnosis of ARDS. The esophageal pressure was monitored using the polyfunctional nasogastric tube (Nutrivent™). The end-expiratory volume was measured using the Carescape R860 (GE Healthcare) by the nitrogen multiple breath wash-out/wash-in (EELV) at a positive end-expiratory pressure of 5. EIT measurements were performed using the Pulmo Vista 500. We performed a recruitment maneuver using the “staircase maneuver.” Results: As per the results of our study, we found that almost 2/3rd (66.7%) of the patients affected with COVID lungs affected with ARDS were recruitable. Conclusion: The results of our study again make us believe that majority of COVID-19 lungs affected with ARDS may be recruitable in the earlier stage of the illness (within the 1st week of ARDS). Thus, in such patients, safe, monitored lung recruitment should be attempted to improve oxygenation rather than directly proning the patient, which is fraught with its own set of complications. |
| first_indexed | 2024-03-12T03:31:15Z |
| format | Article |
| id | doaj.art-d623106480094283be5f5eed0039e142 |
| institution | Directory Open Access Journal |
| issn | 2277-9019 2321-4899 |
| language | English |
| last_indexed | 2024-03-12T03:31:15Z |
| publishDate | 2022-01-01 |
| publisher | Jaypee Brothers Medical Publisher |
| record_format | Article |
| series | Indian Journal of Respiratory Care |
| spelling | doaj.art-d623106480094283be5f5eed0039e1422023-09-03T13:26:28ZengJaypee Brothers Medical PublisherIndian Journal of Respiratory Care2277-90192321-48992022-01-0111324625210.4103/ijrc.ijrc_35_22A retrospective observational study to analyze recruitment paradigms in the treatment of hypoxemic COVID-19 patients admitted in the intensive care unit of a tertiary care institute in IndiaSanjith SaseedharanVaijaynti KadamShalaka PatilAakash SoniAshish YadavRujuta BagadeIpshita PanigrahiNamya MiglaniIntroduction: This retrospective study attempted to assess the recruitability of the lungs that were affected by acute respiratory distress syndrome (ARDS) due to COVID-19. This was done with the combined use of transpulmonary pressure monitoring (to limit the stress), measurement of end-expiratory lung volume (EELV) (to measure the actual volume gain and be within limits of strain), electrical impedance tomography (EIT), and compliance (to diagnose overdistension). Recruitment was judged clinically by an increase in the SpO2 values. Methods: Retrospective data from the charts and progress sheets were collected from 27 patients admitted to the intensive care unit (between February 2021 and June 2021) with a ratio of arterial Partial pressure of oxygen (PaO2 in mmHg) to fractional inspired oxygen (FiO2) <150 (i.e., PaO2/FiO2 <150) with a diagnosis of ARDS. The esophageal pressure was monitored using the polyfunctional nasogastric tube (Nutrivent™). The end-expiratory volume was measured using the Carescape R860 (GE Healthcare) by the nitrogen multiple breath wash-out/wash-in (EELV) at a positive end-expiratory pressure of 5. EIT measurements were performed using the Pulmo Vista 500. We performed a recruitment maneuver using the “staircase maneuver.” Results: As per the results of our study, we found that almost 2/3rd (66.7%) of the patients affected with COVID lungs affected with ARDS were recruitable. Conclusion: The results of our study again make us believe that majority of COVID-19 lungs affected with ARDS may be recruitable in the earlier stage of the illness (within the 1st week of ARDS). Thus, in such patients, safe, monitored lung recruitment should be attempted to improve oxygenation rather than directly proning the patient, which is fraught with its own set of complications.http://www.ijrc.in/article.asp?issn=2277-9019;year=2022;volume=11;issue=3;spage=246;epage=252;aulast=Saseedharanacute respiratory distress syndromecovid-19electrical impedance tomographytranspulmonary pressure |
| spellingShingle | Sanjith Saseedharan Vaijaynti Kadam Shalaka Patil Aakash Soni Ashish Yadav Rujuta Bagade Ipshita Panigrahi Namya Miglani A retrospective observational study to analyze recruitment paradigms in the treatment of hypoxemic COVID-19 patients admitted in the intensive care unit of a tertiary care institute in India Indian Journal of Respiratory Care acute respiratory distress syndrome covid-19 electrical impedance tomography transpulmonary pressure |
| title | A retrospective observational study to analyze recruitment paradigms in the treatment of hypoxemic COVID-19 patients admitted in the intensive care unit of a tertiary care institute in India |
| title_full | A retrospective observational study to analyze recruitment paradigms in the treatment of hypoxemic COVID-19 patients admitted in the intensive care unit of a tertiary care institute in India |
| title_fullStr | A retrospective observational study to analyze recruitment paradigms in the treatment of hypoxemic COVID-19 patients admitted in the intensive care unit of a tertiary care institute in India |
| title_full_unstemmed | A retrospective observational study to analyze recruitment paradigms in the treatment of hypoxemic COVID-19 patients admitted in the intensive care unit of a tertiary care institute in India |
| title_short | A retrospective observational study to analyze recruitment paradigms in the treatment of hypoxemic COVID-19 patients admitted in the intensive care unit of a tertiary care institute in India |
| title_sort | retrospective observational study to analyze recruitment paradigms in the treatment of hypoxemic covid 19 patients admitted in the intensive care unit of a tertiary care institute in india |
| topic | acute respiratory distress syndrome covid-19 electrical impedance tomography transpulmonary pressure |
| url | http://www.ijrc.in/article.asp?issn=2277-9019;year=2022;volume=11;issue=3;spage=246;epage=252;aulast=Saseedharan |
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