Regulation of MT1-MMP Activity through Its Association with ERMs

Regulation of MT1-MMP Activity through Its Association with ERMs

Membrane-bound proteases play a key role in biology by degrading matrix proteins or shedding adhesion receptors. MT1-MMP metalloproteinase is critical during cancer invasion, angiogenesis, and development. MT1-MMP activity is strictly regulated by internalization, recycling, autoprocessing but also...

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Bibliographic Details
Main Authors: Henar Suárez, Soraya López-Martín, Víctor Toribio, Moreno Zamai, M. Victoria Hernández-Riquer, Laura Genís, Alicia G. Arroyo, María Yáñez-Mó
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
mt1-mmp
erm
tetraspanin enriched-microdomains
extracellular vesicles
Online Access:https://www.mdpi.com/2073-4409/9/2/348

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